Dr Sandra Depelsenaire
Adjunct Senior Fellow
School of Chemistry and Molecular Biosciences
Book Chapter
Depelsenaire, A. C. I., Kendall, M. A. F., Young, P. R. and Muller, D. A. (2017). Introduction to vaccines and vaccination. Micro and nanotechnology in vaccine development. (pp. 47-62) edited by Mariusz Skwarczynski and Istvan Toth. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-323-39981-4.00003-8
Journal Articles
Muller, David A., Depelsenaire, Alexandra C. I., Shannon, Ashleigh E., Watterson, Daniel, Corrie, Simon R., Owens, Nick S., Agyei-Yeboah, Christiana, Cheung, Stacey T. M., Zhang, Jin, Fernando, Germain J. P., Kendall, Mark A. F. and Young, Paul R. (2019). Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays. Vaccines, 7 (4) 189, 189. doi: 10.3390/vaccines7040189
Ng, Hwee-Ing, Tuong, Zewen K., Fernando, Germain J. P., Depelsenaire, Alexandra C. I., Meliga, Stefano C., Frazer, Ian H. and Kendall, Mark A. F. (2019). Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses. npj Vaccines, 4 (1) 41, 41. doi: 10.1038/s41541-019-0134-4
van der Burg, Nicole M.D., Depelsenaire, Alexandra C.I., Crichton, Michael L., Kuo, Paula, Phipps, Simon and Kendall, Mark A.F. (2019). A low inflammatory, Langerhans cell-targeted microprojection patch to deliver ovalbumin to the epidermis of mouse skin. Journal of Controlled Release, 302, 190-200. doi: 10.1016/j.jconrel.2019.03.027
Muller, David A., Fernando, Germain J. P., Owens, Nick S., Agyei-Yeboah, Christiana, Wei, Jonathan C. J., Depelsenaire, Alexandra C. I., Forster, Angus, Fahey, Paul, Weldon, William C., Oberste, M. Steven, Young, Paul R. and Kendall, Mark A. F. (2017). High-density microprojection array delivery to rat skin of low doses of trivalent inactivated poliovirus vaccine elicits potent neutralising antibody responses. Scientific Reports, 7 (1) 12644, 12644. doi: 10.1038/s41598-017-13011-0
Muller, David A., Depelsenaire, Alexandra C. I. and Young, Paul R. (2017). Clinical and laboratory diagnosis of dengue virus infection. Journal of Infectious Diseases, 215 (2), S89-S95. doi: 10.1093/infdis/jiw649
Ng, Hwee-Ing, Fernando, Germain J. P., Depelsenaire, Alexandra C. I. and Kendall, Mark A. F. (2016). Potent response of QS-21 as a vaccine adjuvant in the skin when delivered with the Nanopatch, resulted in adjuvant dose sparing. Scientific Reports, 6 (1) 29368, 29368. doi: 10.1038/srep29368
Crichton, Michael Lawrence, Muller, David Alexander, Depelsenaire, Alexandra Christina Isobel, Pearson, Frances Elizabeth, Wei, Jonathan, Coffey, Jacob, Zhang, Jin, Fernando, Germain J. P. and Kendall, Mark Anthony Fernance (2016). The changing shape of vaccination: Improving immune responses through geometrical variations of a microdevice for immunization. Scientific Reports, 6 (1) 27217, e27217.1-e27217.7. doi: 10.1038/srep27217
Depelsenaire, Alexandra C. I., Meliga, Stefano C., McNeilly, Celia, Pearson, Frances E., Coffey, Jacob, Haigh, Oscar L., Flaim, Christopher J., Frazer, Ian H. and Kendall, Mark A. F. (2014). Colocalization of cell death with antigen deposition in skin enhances vaccine immunogenicity. The Journal of Investigative Dermatology, 134 (9), 2361-2370. doi: 10.1038/jid.2014.174
Haigh, Oscar, Depelsenaire, Alexandra C. I., Meliga, Stefano C., Yukiko, Sally R., McMillan, Nigel A. J., Frazer, Ian H. and Kendall, Mark A. F. (2014). CXCL1 gene silencing in skin using liposome-encapsulated siRNA delivered by microprojection array. Journal of Controlled Release, 194, 148-156. doi: 10.1016/j.jconrel.2014.08.021
Corrie, Simon, Depelsenaire, Alexandra and Kendall, Mark (2012). Introducing the nanopatch: a skin-based, needle-free vaccine delivery system. Australian Biochemist, 43 (3), 17-20.
Conference Papers
van der Burg, Nicole M. D., Holt, Patrick G., Phipps, Simon, Crichton, Michael L., Depelsenaire, Alexandra C. and Kendall, Mark A. F. (2016). Taking advantage of tolerance tests in the mouse model to screen alternative microprojection patch designs for allergy immunotherapy. Australasian Society of Clinical Immunology and Allergy (ASCIA) 27th Annual Conference, Gold Coast, Queensland, Australia, 14–17 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.63_13197
Muller, D. A., Depelsenaire, A. C. I., Watterson, D., Zhang, J., Yukiko, S. R., Young, P. R. and Kendall, M. A. F. (2014). Targeted delivery of candidate dengue virus subunit vaccine to the skin using the Nanopatch™. Vaccine Technology V, Playa del Carmen, Mexico, 8-13 June 2014.
Meliga, Stefano, Coffey, J., Raphael, A. P., Depelsenaire, A. C. I., Crichton, M. L., Flaim, A. C., Veidt, M. and Kendall, M. A. F. (2013). Rational design of microprojection array-mediated vaccine delivery to skin, using mathematical modelling and experimental methods. 13AH: Vaccine Delivery and Stabilization: Improving the Reach of Vaccines, Boston, MA, USA, 8-10 September, 2013.
Depelsenaire, A. C. I., Haigh, O. L., Pearson, F., McNeilly, C., Flaim, C. and Kendall, M. A. F. (2013). Co-localizing Nanopatch™-mediated skin damage with adjacent live cells and vaccine enhances systemic immunogenicity.. Skin Vaccination Summit 2011, Seattle, Washington, United States, 4 - 6 September 2013.
Depelsenaire, A., Pearson, F. E., Haigh, O. L. and Kendall, M. A. F (2013). Enhanced systemic immunogenicity achieved by co-localising vaccine with Nanopatch-mediated skin damage adjacent to live cells. Vaccine Delivery and Stabilization: Improving the Reach of Vaccines, Boston, United States, 8-10 September 2013.
Depelsenaire, Alexandra C. I., Watterson, Daniel, Zhang, Jin, Yukiko, Sally, Young, Paul R., Kendall, Mark A. F. and Muller, David A. (2013). Nanopatch delivery of a tetravalent recombinant subunit dengue vaccine. Australasian Virology Society Meeting 2013, Queenstown, New Zealand, 8-11 December 2013.
Pearson, Frances E., Haigh, Oscar L., Depelsenaire, Alexandra, Brunck, Marion E. G. and Kendall, Mark A. F. (2013). The role of polymorphonuclear neutrophils in innate and adaptive responses to Nanopatch delivery of split virion influenza vaccine to skin. Skin Vaccination Summit 2013, Seattle, United States, 4-6 September 2013.
Meliga, S. C., Coffey, J., Raphael, A..P., Depelsenaire, A. C. I., Flaim, C., Veidt, M. and Kendall, M. A. F. (2013). Improving vaccine targeting to skin using mathematical model-driven design and application of microprojection arrays. Skin Vaccination Summit, Seattle, Washington, USA, 4 - 6 September 2013.
Depelsenaire, A. C. I., McNeilly, C., Haigh, O. L., Pearson, F., Flaim, C. and Kendall, M. A. F. (2012). Increased immunogenicity following co-localisation of antigen with cellular damage mediated by Nanopatch™ micro-projections. 1st International Conference on BioNano Innovation (ICBNI), Brisbane, Australia, 18 - 20 July 2012.
Scott, Suzanne, Depelsenaire, Alexandra, Corrie, Simon and Kendall, Mark A. F (2012). Investigating mechanisms of Nanopatch™-mediated biomarker capture in skin.. 3rd Brisbane Early Career Researcher: Poster Symposium, Brisbane, Australia, 20 November 2012. Brisbane, Austalia: The University of Queensand.
Depelsenaire, A., McNeilly, C., Flaim, C. and Kendall, M. (2011). Spatial and quantitative analysis of localized cell death in the skin following Nanopatch™ application. Skin Vaccination Summit 2011, Washington, United States, 12-14 October 2011.
Depelsenaire, A. C. I., McNeilly, C., Flaim, C. and Kendall, M. A. F. (2011). Spacial and quantitative analysis of localised cell death in the skin following Nanopatch™ application. AIBN Student Conference, Brisbane, Australia, 23 - 24 September 2011.
Thesis
Depelsenaire, Alexandra (2014). Investigation of cell death caused by the Nanopatch™ and its role in vaccine delivery as a physical immune enhancer. PhD Thesis, AIBN, The University of Queensland. doi: 10.14264/uql.2015.195
Patent
Kendall, Mark Anthony Fernace, Meliga, Alexandra Christina Isabelle, Depelsenaire, A.C, Crichton, Michael Lawrence and Flaim, Christopher Flaim (2013). Delivery device. WO2013053022-A1.