Biorefineries for Sustainable Chemical Synthesis and Fluorescent Sensors as Tools for Investigating Biological Processes
Abstract
The first half of the presentation will describe our efforts to use a biorefinery based approach to catalytically upgrade biorenewable monoterpene feedstocks (e.g., turpentine, waste citrus oils, eucalyptus oils) into a variety of sustainable commodity chemicals, bioplastics and drugs that are currently derived from non-renewable petrochemical feedstocks.1,2
The second half of the presentation will describe our efforts into developing fluorescent chemical sensors as investigational tools for probing complex biological processes in cellular systems, including for the real-time detection of osteocyte bone resorbing activity in deep bone cavities, imaging of amyloid-beta plaques in mice brains and visualisation of drug induced liver damage.
Selected References
1. Green Chem., 2021, 23, 5449-5455. 2. Green Chem., 2021, 23, 597-610. 3. Adv. Sustain. Syst., 202000292. 4. Chem. Sci., 2022, 13, 1419-1427. 5. J. Am. Chem. Sci., 2022, 144, 174-183. 6. Chem. Sci., 2021, 12, 3921-3928. 7. Chem. Sci., 2021, 12, 2498-2503. 8. ACS Central Sci., 2020, 6, 1813-1818. 9. Angew. Chem. Int. Ed. Engl., 2020, 59, 20996-21000. 10. J. Am. Chem. Sci., 2018, 140, 14267-14271. 11. Chem. Comm., 2017, 53, 10441-10443. 12. Chem. Sci., 2014, 5, 3368-3373.
About School research seminars
Seminars cover all aspects of chemistry and molecular biosciences and are delivered by visiting national and international academics. PhD completion seminars are also incorporated into the program.
Seminars are usually held in person and via zoom. All are welcome to attend.
Contacts
- Chemistry: Dr Rowan Young, Dr David Cantillo
- Molecular Biosciences: Dr Mathew Jones