The unprecedented COVID-19 crisis has led to a worldwide effort to rapidly characterize the virology of SARS-CoV-2, while mitigating further spread of this deadly pathogen. Alongside investigations into the virology of SARS-CoV-2, understanding the fundamental physiological and immunological processes underlying the clinical manifestations of COVID-19 is vital for the identification and rational
design of effective therapies. This talk will provide an overview of the pathophysiology of SARS-CoV-2 infection. I will describe its interaction with the immune system and the subsequent contribution of dysfunctional immune responses to disease progression that provided useful insights in the successful development of vaccines and booster strategies.


Lisa graduated with a BSc (Hons) in Biochemistry from the University of Manchester Institute of Science and Technology (UMIST) in the United Kingdom in 1995. Following this, she then obtained her PhD in Molecular Virology in coronaviruses in 2002. The research interest of her group focuses on the immune responses of arthrogenic arboviruses that are epidemic or highly endemic in the tropical region. These include chikungunya virus, dengue virus, Zika virus, other related alpha- and flavi-viruses. Since 2020, her team has been deeply involved with COVID-19, with a strong focus on infection and immunity. She is current Executive Director of A*STAR’s Infectious Diseases Labs.


About School research seminars

Seminars cover all aspects of chemistry and molecular biosciences and are delivered by visiting national and international academics. PhD completion seminars are also incorporated into the program.

Seminars are usually held in person and via zoom. All are welcome to attend.