MBS Seminar - Acyl-CoA synthetase (ACSL1) is key regulator of insulin secretion and a pathogenetic factor in Type 2 Diabetes

Title: Acyl-CoA synthetase (ACSL1) is key regulator of insulin secretion and a pathogenetic factor in Type 2 Diabetes

Speaker: Professor Hindrik Mulder (Lund University, Sweden)

Bio: Hindrik Mulder is an MD who received his Ph.D in Physiology in 1997. He was a postdoctoral fellow at Southwestern Medical School in Dallas, Texas (1998-2000). In 2000, he was awarded a position as associate professor from the Swedish Research Council. Hindrik Mulder became full professor at the Medical Faculty in Lund 2007. He sees diabetes patients at the Endocrinology Outpatient Unit at Skåne University Hospital. Hindrik Mulder’s current research explores the mechanisms whereby genetic variation influences mitochondrial function, lipid metabolism and circadian regulation in beta-cells in the events leading to Type 2 Diabetes. His group has established a platform for use of induced pluripotent stem cells from patients with Type 2 Diabetes. These cells are differentiated into mature cells in which pathogenic mechanisms in type 2 diabetes are examined. Hindrik Mulder has received the Anna-Greta Crafoord award for best thesis at the Medical Faculty in Lund, Carl Tesdorpf’s award, and the DPLU/LUDC Nordic prize for an Outstanding Young Diabetes Investigator. In 2024, he received the Novo Nordisk Foundation Lecture Prize, recognizing a Nordic scientist’s outstanding contribution within research or treatment related to diabetes. Hindrik Mulder is currently Editor-in-Chief of Diabetologia, and member of the boards of the European Association for the Study of Diabetes (EASD) and the European Foundation for the Study of Diabetes (EFSD).