Associate Professor David Muller

Watterson, Daniel, Modhiran, Naphak, Muller, David A., Stacey, Katryn J. and Young, Paul R. (2018). Plugging the leak in Dengue shock. Dengue and Zika: Control and Antiviral Treatment Strategies. (pp. 89-106) edited by Rolf Hilgenfeld and Subhash G. Vasudevan. Singapore, Singapore: Springer Nature. doi: 10.1007/978-981-10-8727-1_7

Depelsenaire, A. C. I., Kendall, M. A. F., Young, P. R. and Muller, D. A. (2017). Introduction to vaccines and vaccination. Micro and nanotechnology in vaccine development. (pp. 47-62) edited by Mariusz Skwarczynski and Istvan Toth. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-323-39981-4.00003-8

Muller, David and Young, Paul R. (2012). The many faces of the flavivirus non-structural glycoprotein NS1. Molecular virology and control of flaviviruses. (pp. 51-75) edited by Pei-Yong Shi. Norfolk, United Kingdom: Caister Academic Press.

McMillan, Christopher L. D., Wijesundara, Danushka K., Choo, Jovin J. Y., Amarilla, Alberto A., Modhiran, Naphak, Fernando, Germain J. P., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R. and Muller, David A. (2024). Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein. Journal of General Virology, 105 (1) ARTN 001947, 1-6. doi: 10.1099/jgv.0.001947

Wijesundara, Danushka K., Yeow, Arthur, McMillan, Christopher L. D., Choo, Jovin J. Y., Todorovic, Aleksandra, Mekonnen, Zelalem A., Masavuli, Makutiro G., Young, Paul R., Gowans, Eric J., Grubor-Bauk, Branka and Muller, David A. (2023). Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine. Molecular Therapy Nucleic Acids, 34 102056. doi: 10.1016/j.omtn.2023.102056

Tong, Marcus Z. W., Sng, Julian D. J., Carney, Meagan, Cooper, Lucy, Brown, Samuel, Lineburg, Katie E., Chew, Keng Yih, Collins, Neve, Ignacio, Kirsten, Airey, Megan, Burr, Lucy, Joyce, Briony A., Jayasinghe, Dhilshan, McMillan, Christopher L. D., Muller, David A., Adhikari, Anurag, Gallo, Linda A., Dorey, Emily S., Barrett, Helen L., Gras, Stephanie, Smith, Corey, Good‐Jacobson, Kim and Short, Kirsty R. (2023). Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection. Clinical and Translational Immunology, 12 (12) e1476, 1-13. doi: 10.1002/cti2.1476

Baker, Ben, Bermingham, Imogen M., Leelasena, Indika, Hickling, Julian, Young, Paul R., Muller, David A. and Forster, Angus H. (2023). Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial. Vaccines, 11 (11) 1725, 1-17. doi: 10.3390/vaccines11111725

Choo, Jovin J. Y., McMillan, Christopher L. D., Young, Paul R. and Muller, David A. (2023). Microarray patches: scratching the surface of vaccine delivery. Expert Review of Vaccines, 22 (1), 937-955. doi: 10.1080/14760584.2023.2270598

McMillan, Christopher L.D., Amarilla, Alberto A., Modhiran, Naphak, Choo, Jovin J.Y., Azuar, Armira, Honeyman, Kate E., Khromykh, Alexander A., Young, Paul R., Watterson, Daniel and Muller, David A. (2022). Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern. Vaccine, 40 (34), 4929-4932. doi: 10.1016/j.vaccine.2022.07.013

Isaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J. and Watterson, Daniel (2022). Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants. Frontiers in Immunology, 13 926262, 926262. doi: 10.3389/fimmu.2022.926262

Oliveira, Camille F. de, Neto, Walter F. F., Silva, Carla P. da, Ribeiro, Ana Claudia S., Martins, Lívia C., Sousa, Alana W. de, Freitas, Maria N. O., Chiang, Jannifer O., Silva, Franko A., Santos, Eder B. dos, Medeiros, Daniele B. A., Pinheiro, Gleiciane S., Brandão, Gleiciane F., Carvalho, Valéria L., Azevedo, Raimunda S. S., Vasconcelos, Pedro F. C., Costa, Igor B., Costa, Iran B., Santos, Mirleide C. dos, Soares, Luana S., Bedran, Rayssa L. S., Ferreira, James L., Amarilla, Alberto A., Modhiran, Naphak, McMillan, Christopher L. D., Freney, Morgan E., Muller, David A., Watterson, Daniel, Casseb, Lívia M. N. and Henriques, Daniele F. (2022). Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration. Vaccines, 10 (5) 690, 690. doi: 10.3390/vaccines10050690

Iredahl, Fredrik, Muller, David A., Togö, Totte, Jonasson, Hanna, Baker, Ben, Anderson, Chris D. and Henricson, Joakim (2022). Local response and barrier recovery in elderly skin following the application of high-density microarray patches. Vaccines, 10 (4) 583, 583. doi: 10.3390/vaccines10040583

McMillan, Christopher L. D., Azuar, Armira, Choo, Jovin J. Y., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Honeyman, Kate E., Cheung, Stacey T. M., Liang, Benjamin, Wurm, Maria J., Pino, Paco, Kint, Joeri, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Hobson-Peters, Jody, Watterson, Daniel, Young, Paul R. and Muller, David A. (2022). Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern. Vaccines, 10 (4) 578, 578. doi: 10.3390/vaccines10040578

Henricson, Joakim, Muller, David A., Baker, S. Ben, Iredahl, Fredrik, Togö, Totte and Anderson, Chris D. (2022). Micropuncture closure following high density microarray patch application in healthy subjects. Skin Research and Technology, 28 (2), 305-310. doi: 10.1111/srt.13131

Choo, Jovin J. Y., McMillan, Christopher L. D., Fernando, Germain J. P., Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). Developing a stabilizing formulation of a live chimeric dengue virus vaccine dry coated on a high-density microarray patch. Vaccines, 9 (11) 1301, 1301. doi: 10.3390/vaccines9111301

McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Cheung, Stacey T. M., Liang, Benjamin, Bielefeldt-Ohmann, Helle, Azuar, Armira, Acharya, Dhruba, Kelly, Gabrielle, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., McMillan, Nigel A. J. and Muller, David A. (2021). Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine. Science Advances, 7 (44) eabj8065, eabj8065. doi: 10.1126/sciadv.abj8065

Scott, Connor A. P., Amarilla, Alberto A., Bibby, Summa, Newton, Natalee D., Hall, Roy A., Hobson-Peters, Jody, Muller, David A., Chappell, Keith J., Young, Paul R., Modhiran, Naphak and Watterson, Daniel (2021). Implications of dengue virus maturation on vaccine induced humoral immunity in mice. Viruses, 13 (9) 1843, 1843. doi: 10.3390/v13091843

Choo, Jovin J. Y., Vet, Laura J., McMillan, Christopher L. D., Harrison, Jessica J., Scott, Connor A. P., Depelsenaire, Alexandra C. I., Fernando, Germain J. P., Watterson, Daniel, Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice. npj Vaccines, 6 (1) 66, 66. doi: 10.1038/s41541-021-00328-1

Modhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425

Muller, David A., Henricson, Joakim, Baker, S. Ben, Togö, Totte, Jayashi Flores, Cesar M., Lemaire, Pierre A., Forster, Angus and Anderson, Chris D. (2020). Innate local response and tissue recovery following application of high density microarray patches to human skin. Scientific Reports, 10 (1) 18468, 18468. doi: 10.1038/s41598-020-75169-4

Muller, David A., Depelsenaire, Alexandra C. I., Shannon, Ashleigh E., Watterson, Daniel, Corrie, Simon R., Owens, Nick S., Agyei-Yeboah, Christiana, Cheung, Stacey T. M., Zhang, Jin, Fernando, Germain J. P., Kendall, Mark A. F. and Young, Paul R. (2019). Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays. Vaccines, 7 (4) 189, 189. doi: 10.3390/vaccines7040189

Walker, Julia A., Robinson, Kye J., Munro, Christopher, Gengenbach, Thomas, Muller, David A., Young, Paul R., Lua, Linda H. L. and Corrie, Simon R. (2018). Antibody-binding, antifouling surface coatings based on recombinant expression of zwitterionic EK peptides. Langmuir, 35 (5) acs.langmuir.8b00810, 1266-1272. doi: 10.1021/acs.langmuir.8b00810

Muller, David A., Fernando, Germain J. P., Owens, Nick S., Agyei-Yeboah, Christiana, Wei, Jonathan C. J., Depelsenaire, Alexandra C. I., Forster, Angus, Fahey, Paul, Weldon, William C., Oberste, M. Steven, Young, Paul R. and Kendall, Mark A. F. (2017). High-density microprojection array delivery to rat skin of low doses of trivalent inactivated poliovirus vaccine elicits potent neutralising antibody responses. Scientific Reports, 7 (1) 12644, 12644. doi: 10.1038/s41598-017-13011-0

Muller, David A., Depelsenaire, Alexandra C. I. and Young, Paul R. (2017). Clinical and laboratory diagnosis of dengue virus infection. Journal of Infectious Diseases, 215 (2), S89-S95. doi: 10.1093/infdis/jiw649

Lee, Khai T., Coffey, Jacob W., Robinson, Kye J., Muller, David A., Grondahl, Lisbeth, Kendall, Mark A. F., Young, Paul R. and Corrie, Simon R. (2017). Investigating the effect of substrate materials on wearable immunoassay performance. Langmuir, 33 (3), 773-782. doi: 10.1021/acs.langmuir.6b03933

Faddy, H. M., Fryk, J. J., Watterson, D., Young, P. R., Modhiran, N., Muller, D. A., Keil, S. D., Goodrich, R. P. and Marks, D. C. (2016). Riboflavin and ultraviolet light: impact on dengue virus infectivity. Vox Sanguinis, 111 (3), 235-241. doi: 10.1111/vox.12414

Crichton, Michael Lawrence, Muller, David Alexander, Depelsenaire, Alexandra Christina Isobel, Pearson, Frances Elizabeth, Wei, Jonathan, Coffey, Jacob, Zhang, Jin, Fernando, Germain J. P. and Kendall, Mark Anthony Fernance (2016). The changing shape of vaccination: Improving immune responses through geometrical variations of a microdevice for immunization. Scientific Reports, 6 (1) 27217, e27217.1-e27217.7. doi: 10.1038/srep27217

Muller, David A., Pearson, Frances E., Fernando, Germain J. P., Agyei-Yeboah, Christiana, Owens, Nick S., Corrie, Simon R., Crichton, Michael L., Wei, Jonathan C. J., Weldon, William C., Oberste, M. Steven, Young, Paul R. and Kendall, Mark A. F. (2016). Inactivated poliovirus type 2 vaccine delivered to rat skin via high density microprojection array elicits potent neutralising antibody responses. Scientific Reports, 6 (22094) 22094, 1-7. doi: 10.1038/srep22094

Robinson, Kye J., Coffey, Jacob W., Muller, David A., Young, Paul R., Kendall, Mark A., Thurecht, Kristofer J., Grøndahl, Lisbeth and Corrie, Simon R. (2015). Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue. Biointerphases, 10 (4) 04A305, 04A305.1-04A305.11. doi: 10.1116/1.4932055

Pearson, Frances E., Muller, David A., Roalfe, Lucy, Zancolli, Marta, Goldblatt, David and Kendall, Mark A.F. (2015). Functional anti-polysaccharide IgG titres induced by unadjuvanted pneumococcal-conjugate vaccine when delivered by microprojection-based skin patch. Vaccine, 33 (48), 6675-6683. doi: 10.1016/j.vaccine.2015.10.081

Modhiran, Naphak, Watterson, Daniel, Muller, David A., Panetta, Adele K., Sester, David P., Liu, Lidong, Hume, David A., Stacey, Katryn J. and Young, Paul R. (2015). Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Science Translational Medicine, 7 (304) 304ra142, 1-10. doi: 10.1126/scitranslmed.aaa3863

Lee, Khai Tuck, Muller, David A., Coffey, Jacob W., Robinson, Kye J., McCarthy, James S., Kendall, Mark A. F. and Corrie, Simon R. (2014). Capture of the circulating Plasmodium falciparum biomarker HRP2 in a multiplexed format, via a wearable skin patch. Analytical Chemistry, 86 (20), 10474-10483. doi: 10.1021/ac5031682

Yeow, Bernard., Coffey, Jacob W., Muller, David A., Grondahl, Lisbeth, Kendall, Mark A. F. and Corrie, Simon R. (2013). Surface modification and characterization of polycarbonate microdevices for capture of circulating biomarkers, both in vitro and in vivo. Analytical Chemistry, 85 (21), 10196-10204. doi: 10.1021/ac402942x

Muller, David A. and Young, Paul R. (2013). The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker. Antiviral research, 98 (2), 192-208. doi: 10.1016/j.antiviral.2013.03.008

Muller, David A., Frentiu, Francesca D., Rojas, Alejandra, Moriero, Luciano A., O'Neill, Scott L. and Young, Paul R. (2012). A portable approach for the surveillance of dengue virus-infected mosquitoes. Journal of Virological Methods, 183 (1), 90-93. doi: 10.1016/j.jviromet.2012.03.033

Bhargav, Aarshi, Muller, David A., Kendall, Mark A. F. and Corrie, Simon R. (2012). Surface modifications of microprojection arrays for improved biomarker capture in the skin of live mice. ACS Applied Materials and Interfaces, 4 (5), 2483-2489. doi: 10.1021/am3001727

Muller, David A., Corrie, Simon R., Coffey, Jacob, Young, Paul R. and Kendall, Mark A. (2012). Surface modified microprojection arrays for the selective extraction of the dengue virus NS1 protein as a marker for disease. Analytical Chemistry, 84 (7), 3262-3268. doi: 10.1021/ac2034387

Muller, David A., Landsberg, Michael J., Bletchly, Cheryl, Rothnagel, Rosalba, Waddington, Lynne, Hankamer, Ben and Young, Paul R. (2012). Structure of the dengue virus glycoprotein non-structural protein 1 by electron microscopy and single-particle analysis. Journal of General Virology, 93 (4), 771-779. doi: 10.1099/vir.0.039321-0

Woolford, D. S., Ericksson, G. B., Rothnagel, R., Muller, D., Landsberg, M. J., Pantelic, R., McDowall, A. W., Pailthorpe, B., Young, P. R., Hankamer, B. and Banks, J. (2007). SwarmPS: Rapid, semi-automated single particle selection software. Journal of Structural Biology, 157 (1), 174-188. doi: 10.1016/j.jsb.2006.04.006

Pantelic, R. S., Rothnagel, A. R., Huang, C. Y., Muller, D. A., Woolford, D., Landsberg, M. J., McDowall, A. W., Pailthorpe, B., Young, P. R., Banks, J. E., Hankamer, B. and Ericksson, G. B. (2006). The discriminative bilateral filter: An enhanced denoising filter for electron microscopy data. Journal Of Structural Biology, 155 (3), 395-408. doi: 10.1016/j.jsb.2006.03.030

Muller, D. A., Depelsenaire, A. C. I., Watterson, D., Zhang, J., Yukiko, S. R., Young, P. R. and Kendall, M. A. F. (2014). Targeted delivery of candidate dengue virus subunit vaccine to the skin using the Nanopatch™. Vaccine Technology V, Playa del Carmen, Mexico, 8-13 June 2014.

Depelsenaire, Alexandra C. I., Watterson, Daniel, Zhang, Jin, Yukiko, Sally, Young, Paul R., Kendall, Mark A. F. and Muller, David A. (2013). Nanopatch delivery of a tetravalent recombinant subunit dengue vaccine. Australasian Virology Society Meeting 2013, Queenstown, New Zealand, 8-11 December 2013.

Muller, D. A. and Young, P. R. (2006). Development and characterization of a novel signal peptide for baculorvirus protein production. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Qld, 2-6 July, 2006.

Muller, D. A., Huang, C. and Young, P. R. (2005). Development and characterisation of a novel signal peptide for baculovirus protein production. 3rd Australian Virology Group Mtg, Phillip Is, 9-12 Dec, 2005.

Muller, David A. (2010). Dengue virus non-structural protein NS1: Structure, intracellular trafficking and role as a diagnostic marker. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2017.787

Associate Professor David Muller

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Thesis

Areas of research