Emerita Professor Mary Garson
Primary research interest
Organic Chemistry - chemistry and bioactivity of natural products
Additional profile page
RSC 175 Faces of Chemistry profile page
About me
After graduating with a PhD from the University of Cambridge in 1977, I was an Overseas Research Fellow of the Royal Society in Rome, Italy (1977-1978), a Research Fellow at New Hall, Cambridge (1978-1981) and a Queen Elizabeth II Research Fellow at James Cook University of North Queensland (1983-1985). I have worked in the UK pharmaceutical industry (Smith Kline Beecham) and previously held a lecturing position at The University of Wollongong (1986-1990). I joined The University of Queensland in 1990 and was appointed to a professorship in 2006. I was Deputy Head of School 2005-2009 and retired from my formal teaching and research role in 2020.
I have held leadership positions within the Royal Australian Chemical Institute as the first female President of the Queensland branch (1996-1997), and as Chair of the International Relations Committee (1996-2004). My contributions within the International Union of Pure and Applied Chemistry (IUPAC), the global body representing chemistry, have included membership of Division III (organic and biomolecular) since 2006, including as Division President (2014-2015), and as an elected Member of the IUPAC Bureau (2018-2021). I am currently Vice-President/President-elect for 2024-2025, and will assume the Presidency of IUPAC for the 2026-2027 biennium.
The marine flatworm Maritigrella marygarsonae is named in my honour. In 2024, the Royal Australian Chemical Institute named its award for mid-career researchers in organic chemistry as the Mary Garson Medal.
Research focus and collaborations
My research explores the chemistry and natural bioactivity of secondary metabolites from both the marine and terrestrial environment. A key area of interest are the biosynthetic processes by which terpene metabolites are formed in marine sponges, and particularly in the role of inorganic cyanide and thiocyanate in the generation of the isocyano and isothiocyanato motif found in a number of these metabolites. We have also explored the chemistry and chemical ecology of bioactive 3 alkylpiperidine metabolites from marine sponges, and the chemistry of nudibranchs, notably those from the genera Phyllidiella and Chromodoris, that associate with sponges. An additional interest has been the structure elucidation of metabolites from marine fungi and bacteria. Research into the chemistry of medicinal plants is carried out in collaboration with colleagues from South East Asia.
Funded projects
- The Australia and Pacific Science Foundation Grant with Karen Cheney and Justin Marshall
- 2014 - 2017 "Understanding colour and chemical diversity in marine molluscs". Total value of grant; $46,539
- ARC Discovery grants with Professor Martin Banwell, Research School of Chemistry, ANU
- 2011 - 2014 ARC Discovery Project Grant (with Australian National University), "Synthesis and biological evaluation of Australian sponge metabolites". Total value of grant; $720,000.
- 2007 - 2009 ARC Discovery Project Grant (with Australian National University), "Total synthesis and biological evaluation of Australian sponge metabolites". Total value of grant; $554,736.
- 2004 - 2006 ARC Discovery Project Grant (with Australian National University). "Synthetic molecular and biological studies on novel marine metabolites isolated from Great Barrier Reef sponges". Total value of grant: $600,000.
Achievements and awards
- Elected Fellow of the Australian Academy of Science, 2024.
- The Royal Australian Chemical Institute named its mid-career medal for organic chemists as the Mary Garson medal
- Awarded the Distinguished Fellowship of the Royal Australian Chemical Institute, 2023
- Special issue of the Journal of Natural Products in my honour, March 2023
- Member, Order of Australia for services to education, particularly to organic chemistry, and as a champion for women in science, 2019.
- Australasian section Lecturer, The Royal Society of Chemistry, 2018
- Excellence in Leadership award, The University of Queensland, 2018
- Elected member, Bureau of International Union of Pure and Applied Chemistry (IUPAC), for 2018-2019
- Member of award-winning first year chemistry teaching team- Australian Awards for University Teaching award for Programs that Enhance Learning (Innovation and Flexibility in Curricula, Learning and Teaching category) (2017); winner of University of Queensland award for Programs that Enhance Learning (2016)
- Inaugural recipient, Margaret Sheil Women in Chemistry Leadership Award of the Royal Australian Chemical Institute, 2017
- Division III (organic and biomolecular), International Union of Pure and Applied Chemistry (IUPAC), for 2014-2015; Past President 2016-2017; Secretary 2008-2011; Titular member 2006-2017
- Named as one of the "175 Faces of Diversity" by the Royal Society of Chemistry (UK) in 2014
- Received a Distinguished Woman in Chemistry or Chemical Engineering Award by IUPAC in 2013
- Awarded the 2012 Leighton Memorial Medal for distinguished service to the Royal Australian Chemical Institute
- Member, International Editorial Advisory Board, Phytochemistry
- Member, International Editorial Advisory Board, Journal of Natural Products
- Chair of Board, Australian Science Innovations, 2004-2005
- Chair of Board, Australian Science Olympiads, 2002-2004
- Member, Australian delegation to the World Conference on Science (UNESCO), Budapest, 1999
- Executive Secretary, World Chemistry Congress, held in Brisbane in 2001
- Chair, International Relations Committee of RACI, 1996-2004
- Member, National Committee for Chemistry, 1995-2004
- President, Queensland branch and Member of Full Council of RACI, 1996-1997
Reflections on my teaching and research
My last year of teaching (2020) was dominated by Zoom sessions, but this online format was very suitable for the problem-based classes on NMR spectroscopy. Using an electronic whiteboard, I could easily work with the students on solving NMR datasets.
Over more than 30 years of teaching, technology has shifted from talk and chalk (hampered by chalk dust under my contact lenses on more than one occasion) to hand-written transparencies on an overhead projector to Powerpoint and finally to Zoom. During that time, I have taught science students, medical and pharmacy students, and even the very last generation of engineering students to take CHEM1010. It is quite likely that I taught chemistry to more than ten thousand undergraduates.
During my time at UQ, I undertook 25 research-based expeditions to Heron Island Research Station, and two expeditions to Lizard Island Research Station. In recent years, research diving activities have been based on the Sunshine Coast, with field work at the Gneerings Reef and at Mudjimba Island. In all I completed over 300 research-related dives while an active UQ staff member. I am honoured that the marine flatworm Maritigrella marygarsonae is named after me; I was the first person to collect this new species of flatworm.
Activity since retiring
I have been writing manuscripts and completing the supervision of my final HDR students. I participate in research meetings and attend SCMB functions.
I was the inaugural chair of the IUPAC Committee for Ethics, Diversity, Equity and Inclusion during the 2022-2023 biennium. From January 2024 onwards, I am Vice-President/President-Elect of IUPAC and a Member of its Executive Board. I also chair the Science Board.
Featured publications
- Mollo, Ernesto, Boero, Ferdinando, Peñuelas, Josep, Fontana, Angelo, Garson, Mary J., Roussis, Vassilios, Cerrano, Carlo, Polese, Gianluca, Cattaneo, Alberto Maria, Mudianta, I. Wayan, Genta-Jouve, Gregory, Taglialatela-Scafati, Orazio, Appendino, Giovanni, Amodeo, Pietro and Ghiselin, Michael T. (2022). Taste and Smell: A Unifying Chemosensory Theory. Quarterly Review of Biology, 97 (2), 69-94. doi: 10.1086/720097
- Forster, Louise C., Pierens, Gregory K., Clegg, Jack K. and Garson, Mary J. (2020). Dynamic NMR and computational studies inform the conformational description of dendrillane terpenes from the nudibranch Goniobranchus coi. Journal of Natural Products, 83 (3) acs.jnatprod.9b01051, 714-719. doi: 10.1021/acs.jnatprod.9b01051
- Giordano, Giuseppe, Carbone, Marianna, Ciavatta, Maria Letizia, Silvano, Eleonora, Gavagnin, Margherita, Garson, Mary J., Cheney, Karen L., Mudianta, I Wayan, Russo, Giovanni Fulvio, Villani, Guido, Magliozzi, Laura, Polese, Gianluca, Zidorn, Christian, Cutignano, Adele, Fontana, Angelo, Ghiselin, Michael T. and Mollo, Ernesto (2017) Volatile secondary metabolites as aposematic olfactory signals and defensive weapons in aquatic environments. Proceedings of the National Academy of Sciences of the United States of America, 114 13: 3451-3456. doi:10.1073/pnas.1614655114
- White, Andrew M., Dao, Kathy, Vrubliauskas, Darius, Könst, Zef A., Pierens, Gregory K., Mándi, Attila, Andrews, Katherine T., Skinner-Adams, Tina S., Clarke, Mary E., Narbutas, Patrick T., Sim, Desmond C.-M., Cheney, Karen L., Kurtán, Tibor, Garson, Mary J. and Vanderwal, Christopher D. (2017) Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1. Journal of Organic Chemistry, 82 24: 13313-13323. doi:10.1021/acs.joc.7b02421
- Forster, Louise C., Pierens, Gregory K., White, Andrew M., Cheney, Karen L., Dewapriya, Pradeep, Capon, Robert J. and Garson, Mary J. (2017) Cytotoxic spiroepoxide lactone and its putative biosynthetic precursor from Goniobranchus Splendidus. ACS Omega, 2 6: 2672-2677. doi:10.1021/acsomega.7b00641