Dr Rhys Parry

Research Fellow

School of Chemistry and Molecular Biosciences

r.parry@uq.edu.au

Primary research interest

RNA virus diversity and evolution, connecting viral genetics with host immunity to guide vaccine and RNA design.

About me

I am a molecular virologist and bioinformatician who combines experimental virology, reverse genetics, phylogenetics and high-throughput sequencing to understand RNA virus evolution, host range and immune evasion. I completed my PhD at The University of Queensland studying mosquito viromes and Wolbachia–virus interactions (with Prof. Sassan Asgari), and in 2021 I joined Prof. Alexander Khromykh’s RNA Virology Laboratory.

A central focus of my work is virus discovery and experimental characterisation across diverse hosts. This includes the identification and validation of multiple novel viruses using cell culture systems and molecular virology approaches. My research integrates virus discovery and evolutionary genomics with mechanistic studies in relevant model systems, including PC3 pathogens (JEV, SARS-CoV-2 and WNV), to identify host and viral determinants of replication and pathogenesis. I also use phylogenetics and comparative genomics to support in silico antigen design for vaccine development. In 2026, I commenced my ARC DECRA Fellowship investigating how modified nucleotides shape RNA structure, innate immune sensing, and performance in next-generation RNA technologies, particularly self-amplifying RNA platforms.

Research focus and collaborations

My research spans four connected themes:

Host–virus interactions: understanding how RNA viruses adapt across hosts and how innate immune and RNAi pathways shape infection outcomes.
Virus evolution and diversity: discovering and characterising novel viruses across under-sampled hosts and environments, and applying comparative genomics to define evolutionary constraints, host associations, and emergence potential.
Particular interest in Orthoflavivirus evolution and diversity and influenza evolution and diversity.
Reverse genetics and experimental evolution: developing CPER-based systems, reporter viruses, and replicons for mechanistic studies and rapid hypothesis testing alongside deep mutational scanning approaches for viral evolution experiments.
RNA platforms and applications: developing RNA-based technologies, including self-amplifying RNA, RNAi, and dsRNA tools, for vaccines, protein expression, and therapeutics. A particular interest is how RNA sequence design and nucleotide modifications tune stability, activity, and innate immune recognition.

I welcome collaborations aligned with these themes, particularly projects involving small-RNA analysis, phylogenetics, virus discovery and profiling. I collaborate on the development of reverse-genetics systems for positive-sense RNA viruses and, with access to a broad panel of Risk Group 2/3 orthoflaviviruses and alphaviruses, can support hypothesis and compound-testing, including evaluation of RNA delivery formulations, in relevant ex vivo and organoid-based models.

Collaborators

Dr. Natalee Newton, SCMB, The University of Queensland — Orthoflavivirus structural diversity and evolution and vaccine antigen design (MRFF EMCR Grant 2023)
Dr. Christopher McMillan, SCMB, The University of Queensland — Rational design and development of self-amplifying RNA and RNA therapeutics (NHMRC Ideas Grant 2026)
Prof. Alain Kohl, Liverpool School of Tropical Medicine — Viral RNAi across diverse arbovirus vector organisms
Prof. Esther Schnettler, University of Hamburg/German Centre for Infection Research — Viral RNAi across diverse arbovirus vector organisms
Dr. Mary Petrone, University of Sydney — Virus diversity and evolution, particularly of Orthomyxoviridae

Funded projects

ARC DECRA (2026–2028): Better RNA: modified nucleotides for next-generation RNA technologies
NHMRC Ideas Grant (Chief Investigator (CI) B, 2026–2028): Future RNA therapeutics: a dual-action self-amplifying RNA platform
Animal Disease Genomics Initiative, Bioplatforms Australia (2025): Metagenomics of Australian paralysis ticks
UQ HERA Collaborate Fund (2025–2026): Self-Optimising saRNA: CRISPR-Based Discovery of Host Restriction Factors in Muscle and Liver Models
NHMRC Ideas Grant (CIB, 2025–2028): Lost in translation: why flaviviruses induce cleavage of tRNAs
MRFF EMCR Scheme (CI, 2022–2024): Broad-spectrum vaccine design for flaviviruses and henipaviruses

Achievements and awards

2025 Australian Society for Microbiology Early Career Award (Jim Pittard Award)
2025 Early and Mid-Career Researchers Talk Award, HCV-Flavi2025 (Singapore)
2023 Dean’s Award for Outstanding PhD Thesis (UQ)

Featured publications

Parry RH, Yamada KYH, Hood WR, Zhao Y, Lu JY, Seluanov A, Gorbunova V, Modhiran N, Watterson D, Isaacs A. Henipavirus in Northern Short-Tailed Shrew, Alabama, USA. Emerging Infectious Diseases 2025; 31(2):392–394. doi:10.3201/eid3102.241155

Reuter M*, Parry RH*, McFarlane M, Gestuveo RJ, Arif R, Khromykh AA, Brennan B, Varjak M, Castello A, Redecke L, Schnettler E, Kohl A. The PAZ domain of Aedes aegypti Dicer 2 is critical for accurate and high-fidelity size determination of virus-derived small interfering RNAs. RNA 2025; 31(5):679–691. doi:10.1261/rna.080149.124

Parry RH, McMillan CLD, Bruce KL, Farrell HE. Global transcriptional reprogramming by cytomegalovirus infection suppresses MHC class II antigen presentation while enhancing migration machinery in murine dendritic cells. Microbial Genomics 2025; 11(11):001563. doi:10.1099/mgen.0.001563

Petrone ME, Parry R, Mifsud JCO, Van Brussel K, Vorhees IEH, Richards ZT, Holmes EC. Evidence for an ancient aquatic origin of the RNA viral order Articulavirales. Proceedings of the National Academy of Sciences USA 2023; 120(45):e2310529120. doi:10.1073/pnas.2310529120

Slonchak A, Parry R, Pullinger B, Sng JDJ, Wang X, Buck TF, Torres FJ, Harrison JJ, Colmant AMGC, Hobson-Peters J, Hall RA, Tuplin A, Khromykh AA. Structural analysis of 3'UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution. Nature Communications 2022; 13:1279. doi:10.1038/s41467-022-28977-3

Gestuveo RJ*, Parry R*, Dickson LB, Lequime S, Sreenu VB, Arnold MJ, Khromykh AA, Schnettler E, Lambrechts L, Varjak M*, Kohl A*. Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs. PLoS Pathogens 2022; 18(1):e1010202. doi:10.1371/journal.ppat.1010202

Amarilla AA*, Sng JDJ*, Parry R*, Deerain JM*, Potter JR*, Setoh YX*, Rawle DJ, Le TT, Modhiran N, Wang X, Peng NYG, Torres FJ, Pyke A, Harrison JJ, Freney ME, Liang B, McMillan CLD, Cheung STM, Da Costa Guevara DJ, Hardy JM, Bettington M, Muller DA, Coulibaly F, Moore F, Hall RA, Young PR, Mackenzie JM, Hobson-Peters J, Suhrbier A, Watterson D, Khromykh AA. A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nature Communications 2021; 12:3431. doi:10.1038/s41467-021-23779-5

Parry R, Gifford RJ, Lytras S, Ray SC, Coin LJM. No evidence of SARS-CoV-2 reverse transcription and integration as the origin of chimeric transcripts in patient tissues [Comment]. Proceedings of the National Academy of Sciences USA 2021; 118(33):e2109066118. doi:10.1073/pnas.2109066118

Parry R*, Wille M*, Turnbull OMH, Geoghegan JL, Holmes EC. Divergent influenza-like viruses of amphibians and fish support an ancient evolutionary association. Viruses 2020; 12(9):1042. doi:10.3390/v12091042

Parry R, Asgari S. Discovery of novel crustacean and cephalopod flaviviruses: insights into the evolution and circulation of flaviviruses between marine invertebrate and vertebrate hosts. Journal of Virology 2019; 93(14):e00432-19. doi:10.1128/JVI.00432-19

Researcher biography

I am a molecular virologist and ARC DECRA Fellow at the School of Chemistry and Molecular Biosciences, where I am Deputy Team Leader of the Infection and Immunity theme. My research focuses on RNA virus evolution, host immunity, and RNA technologies for vaccines and therapeutics, linking four connected themes:

Virus discovery and evolution: identifying and characterising novel viruses across diverse hosts using metatranscriptomics, phylogenetics, and comparative genomics, with particular focus on orthoflaviviruses and orthomyxoviruses
Host–virus interactions: understanding how innate immune and RNAi pathways shape infection outcomes in mammalian and arthropod systems
Reverse genetics: developing CPER-based systems, reporter viruses, and replicons for mechanistic virology and rapid hypothesis testing
RNA platforms: engineering self-amplifying RNA to tune stability, expression, and immune sensing for vaccines and therapeutics

I completed my PhD (2016–2021) at UQ's School of Biological Sciences under Prof. Sassan Asgari, where I characterised the virome of Aedes mosquitoes and their interactions with the endosymbiont Wolbachia. In 2021, I joined Prof. Alexander Khromykh's RNA Virology Laboratory at SCMB. There, I contributed to the development of the SARS-CoV-2 CPER reverse-genetics system and have worked routinely with PC3 pathogens, including West Nile virus, Japanese encephalitis virus, and SARS-CoV-2. In 2026, I commenced an ARC DECRA Fellowship to investigate how modified nucleotides shape RNA structure, immune sensing, and function in next-generation RNA technologies. My current work is funded by the ARC and NHMRC.

I provide bioinformatics and phylogenetics support within UQ and internationally, and welcome collaborations involving small RNA analysis, virus discovery and metatranscriptomics.

I served on the organising committee of MicroSeq (2023–2025), an Australasian conference promoting microbial sequencing research by early-career researchers. I am the Communications Officer for ASM Queensland (2024–) and an incoming Committee of Management member for the Australasian Virology Society (2026–).

Publications

Journal Articles (61)

Thesis (1)

Journal Articles

Parry, Rhys H, McMillan, Christopher L D, Bruce, Kimberley L and Farrell, Helen E (2025). Global transcriptional reprogramming by cytomegalovirus infection suppresses MHC class II antigen presentation while enhancing migration machinery in murine dendritic cells. Microbial genomics, 11 (11) 001563. doi: 10.1099/mgen.0.001563

Koutsakos, Marios, Parry, Rhys H. and Wille, Michelle (2025). Mounting evidence for an expanded host range of influenza B viruses. Viruses, 17 (12) 1528, 1528. doi: 10.3390/v17121528

El Ghoubali, Douae, Parry, Rhys H., Pirro, Stacy, Hamdi, Salsabil, Habib, Nihal, El Jaoudi, Rachid, Bousta, Dalila, Barrijal, Said, Nejjari, Chakib, Al Idrissi, Najib, Belyamani, Lahcen and Ghazal, Hassan (2025). Genomic analysis of Androctonus mauritanicus toursvirus: first evidence of Ascoviridae in arachnids. Virus genes, 61 (6), 733-741. doi: 10.1007/s11262-025-02197-5

Hug, Laura A., Hatzenpichler, Roland, Moraru, Cristina, Soares, André R., Meyer, Folker, Heyder, Anke, Zwirzitz, B., Ziels, R. M., Zhu, J., Zhang, Y., Xiu, W., Wu, M., Woyke, T., Worden, A. Z., Williams, T. A., Williams, C. L., Wichels, A., Weissman, J. L., Weiss, L. C., Weir, T., Wegner, C. E., Wang, Y., Wang, S., Walsh, C. J., Wagner, M., von Meijenfeldt, F. A.B., Vierheilig, J., Vázquez-Campos, X., Valentin-Alvarado, L. E. ... Probst, Alexander J. (2025). A roadmap for equitable reuse of public microbiome data. Nature Microbiology, 10 (10), 2384-2395. doi: 10.1038/s41564-025-02116-2

Parry, Rhys H., Shang, Yingjun, Sng, Julian D. J., McMillan, Christopher L. D., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Liang, Benjamin, Muller, David A., Rawle, Daniel J., Suhrbier, Andreas, Anderson, Stevie, Kelly, Samuel, Watterson, Daniel, Burr, Lucy D. and Khromykh, Alexander A. (2025). Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022). Journal of Medical Virology, 97 (10) e70642, 1-15. doi: 10.1002/jmv.70642

Hussain, Mazhar, Etebari, Kayvan, Parry, Rhys H., Khromykh, Alexander A., Hugo, Leon E. and Asgari, Sassan (2025). Transcriptomic response of mosquitoes to Japanese encephalitis virus and identification of its potential entry factors. npj Viruses, 3 (1) 68, 68-1. doi: 10.1038/s44298-025-00151-8

Isaacs, Ariel, Nieto, Guillermo Valenzuela, Zhang, Xinghai, Modhiran, Naphak, Barr, Jennifer, Thakur, Nazia, Low, Yu Shang, Parry, Rhys H., Barnes, James B., Jara, Ronald, Himelreichs, Johanna, Yao, Yanfeng, Deride, Camila, Barthou-Gatica, Barbara, Salinas-Rebolledo, Constanza, Ehrenfeld, Pamela, Hen, Jun Jet, Hayes, Noah, Paramitha, Devina, Morgan, Mahali S., McMillan, Christopher L. D., Jones, Martina L., Munro, Trent P., Khromykh, Alexander A., Reading, Patrick C., Young, Paul R., Chappell, Keith J., Shi, Yi, Bailey, Dalan ... Watterson, Daniel (2025). A nanobody-based therapeutic targeting Nipah virus limits viral escape. Nature Structural and Molecular Biology, 32 (10), 1920-1931. doi: 10.1038/s41594-025-01598-2

Petrone, Mary E., Grove, Joe, Parry, Rhys H., Van Brussel, Kate, Mifsud, Jonathon C.O., Dindar, Zuhairah, Mei, Shi-qiang, Shi, Mang, Turnbull, Olivia M.H., Marzinelli, Ezequiel M. and Holmes, Edward C. (2025). Tunicate metatranscriptomes reveal evidence of ancient co-divergence between viruses and their hosts. Current Biology, 35 (13), 3035-3047. doi: 10.1016/j.cub.2025.05.032

Valle, Coralie, Parry, Rhys H., Coutard, Bruno and Colmant, Agathe M. G. (2025). Discovery of additional genomic segments reveals the fluidity of jingmenvirus genomic organisation. Virus Evolution, 11 (1) veaf023, 1-15. doi: 10.1093/ve/veaf023

Dummunee, Krittika, Parry, Rhys H., Redecke, Lars, Varjak, Margus, Brennan, Benjamin, Kohl, Alain and McFarlane, Melanie (2025). The catalytic tetrad of Aedes aegypti Argonaute 2 is critical for the antiviral activity of the exogenous siRNA pathway. Journal of Biological Chemistry, 301 (4) 108332, 108332. doi: 10.1016/j.jbc.2025.108332

McMillan, Christopher L.D., Corner, Andrea V., Wijesundara, Danushka K., Choo, Jovin J.Y., Pittayakhajonwut, Daraporn, Poredi, Indrajeet, Parry, Rhys H., Bindra, Guneet K., Bruce, Kimberley, Khromykh, Alexander A., Fernando, Germain J.P., Dapremont, Laurent, Young, Paul R. and Muller, David A. (2025). Skin patch delivery of a SARS-CoV-2 Spike DNA vaccine produces broad neutralising antibody responses. Heliyon, 11 (4) e42533, e42533. doi: 10.1016/j.heliyon.2025.e42533

Reuter, Melinda, Parry, Rhys H., McDonald, Melanie, Gestuveo, Rommel J., Arif, Rozeena, Khromykh, Alexander A., Brennan, Benjamin, Varjak, Margus, Castello, Alfredo, Redecke, Lars, Schnettler, Esther and Kohl, Alain (2025). The PAZ domain of Aedes aegypti Dicer 2 is critical for accurate and high-fidelity size determination of virus-derived small interfering RNAs. RNA, 31 (5), 679-691. doi: 10.1261/rna.080149.124

Parry, Rhys H., Yamada, KayLene Y.H., Hood, Wendy R., Zhao, Yang, Lu, Jinlong Y., Seluanov, Andrei, Gorbunova, Vera, Modhiran, Naphak, Watterson, Daniel and Isaacs, Ariel (2025). Henipavirus in northern short-tailed shrew, Alabama, USA. Emerging Infectious Diseases, 31 (2), 392-394. doi: 10.3201/eid3102.241155

Hug, Laura A., Hatzenpichler, Roland, Moraru, Cristina, Soares, André R., Meyer, Folker, Heyder, Anke, Zwirzitz, B., Ziels, R. M., Zhu, J., Zhang, Y., Xiu, W., Wu, M., Woyke, T., Worden, A. Z., Williams, T. A., Williams, C. L., Wichels, A., Weissman, J. L., Weiss, L. C., Weir, T., Wegner, C. E., Wang, Y., Wang, S., Walsh, C. J., Wagner, M., von Meijenfeldt, F. A.B., Vierheilig, J., Vázquez-Campos, X., Valentin-Alvarado, L. E. ... Probst, Alexander J. (2025). Author Correction: A roadmap for equitable reuse of public microbiome data (Nature Microbiology, (2025), 10, 10, (2384-2395), 10.1038/s41564-025-02116-2). Nature Microbiology, 11 (1), 335-335. doi: 10.1038/s41564-025-02212-3

Alexander, Akira J. T., Parry, Rhys H., Ratinier, Maxime, Arnaud, Frédérick and Kohl, Alain (2024). The RNA interference response to alphanodavirus replication in Phlebotomus papatasi sand fly cells. Insect Molecular Biology, 33 (6), 687-696. doi: 10.1111/imb.12932

Dornbusch, Susann, Reuter, Melinda, Parry, Rhys H., Stern, Michael, Becker, Stefanie C. and Schnettler, Esther (2024). Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection. Journal of General Virology, 105 (11) 002046. doi: 10.1099/jgv.0.002046

Parry, Rhys H., Lytras, Spyros, Petrone, Mary E., Wille, Michelle, Crits-Christoph, Alexander, Gifford, Robert J., Saito, Akatsuki, Smura, Teemu and Peacock, Thomas P. (2024). No evidence that mutations in SARS-CoV-2 variants of concern derive from homologous fragments in gut microbiota. Journal of Virology, 98 (12), 1-2. doi: 10.1128/jvi.01468-24

Bell, Mikaela G., Parry, Rhys H., Lee, Tricia S. E., Habarugira, Gervais, McMahon, Isabella E., Thompson, Madeline A., Modhiran, Naphak, Watterson, Daniel, Batovska, Jana, Lynch, Stacey E., Hall, Roy A., Harrison, Jessica J. and Hobson-Peters, Jody (2024). Synthetic recovery of Yada Yada virus expands insect-specific alphavirus knowledge and facilitates production of chimeric viruses. npj Viruses, 2 (1) 45, 1-14. doi: 10.1038/s44298-024-00052-2

Quek, Shannon, Hadermann, Amber, Wu, Yang, De Coninck, Lander, Hegde, Shrilakshmi, Boucher, Jordan R., Cresswell, Jessica, Foreman, Ella, Steven, Andrew, LaCourse, E. James, Ward, Stephen A., Wanji, Samuel, Hughes, Grant L., Patterson, Edward I., Wagstaff, Simon C., Turner, Joseph D., Parry, Rhys H., Kohl, Alain, Heinz, Eva, Otabil, Kenneth Bentum, Matthijnssens, Jelle, Colebunders, Robert and Taylor, Mark J. (2024). Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts. Nature Microbiology, 9 (10), 2488-2505. doi: 10.1038/s41564-024-01796-6

Jansen van Vuren, Petrus, Parry, Rhys H. and Pawęska, Janusz T. (2024). Detection of Dengue virus 1 and mammalian orthoreovirus 3, with novel reassortments, in a South African family returning from Thailand, 2017. Viruses, 16 (8) 1274, 1274. doi: 10.3390/v16081274

Petrone, Mary E., Grove, Joe, Mélade, Julien, Mifsud, Jonathon C. O., Parry, Rhys H., Marzinelli, Ezequiel M. and Holmes, Edward C. (2024). A ~40-kb flavi-like virus does not encode a known error-correcting mechanism. Proceedings of the National Academy of Sciences, 121 (30) e2403805121, e2403805121. doi: 10.1073/pnas.2403805121

Hinds, Joseph, Apaa, Ternenge, Parry, Rhys H., Withers, Amy J., MacKenzie, Laura, Staley, Ceri, Morrison, Joshua, Bennett, Malcolm, Bremner-Harrison, Samantha, Chadwick, Elizabeth A., Hailer, Frank, Harrison, Stephen W.R., Lambin, Xavier, Loose, Mathew, Mathews, Fiona, Tarlinton, Rachael and Blanchard, Adam (2024). Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom. Access Microbiology, 6 (7) 000813.v4, 1-8. doi: 10.1099/acmi.0.000813.v4

Wang, Lan-Lan, Cheng, Qia, Newton, Natalee D., Wolfinger, Michael T., Morgan, Mahali S., Slonchak, Andrii, Khromykh, Alexander A., Cheng, Tian-Yin and Parry, Rhys H. (2024). Xinyang flavivirus, from Haemaphysalis flava ticks in Henan Province, China, defines a basal, likely tick-only Orthoflavivirus clade. Journal of General Virology, 105 (5) 001991, 1-13. doi: 10.1099/jgv.0.001991

Mifsud, Jonathon C. O., Hall, Jane, Van Brussel, Kate, Rose, Karrie, Parry, Rhys H., Holmes, Edward C. and Harvey, Erin (2024). A novel papillomavirus in a New Zealand fur seal (Arctocephalus forsteri) with oral lesions. npj Viruses, 2 (1) 10, 1-10. doi: 10.1038/s44298-024-00020-w

Parry, Rhys H., Slonchak, Andrii, Campbell, Lewis J., Newton, Natalee D., Debat, Humberto J., Gifford, Robert J. and Khromykh, Alexander A. (2023). A novel tamanavirus (Flaviviridae) of the European common frog (Rana temporaria) from the UK. Journal of General Virology, 104 (12) 001927, 1-12. doi: 10.1099/jgv.0.001927

Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L. and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology, 34 (2) cwad097, 1-13. doi: 10.1093/glycob/cwad097

Stewart, Romal, Yan, Kexin, Ellis, Sevannah A., Bishop, Cameron R., Dumenil, Troy, Tang, Bing, Nguyen, Wilson, Larcher, Thibaut, Parry, Rhys, Sng, Julian De Jun, Khromykh, Alexander A., Sullivan, Robert K. P., Lor, Mary, Meunier, Frédéric A., Rawle, Daniel J. and Suhrbier, Andreas (2023). SARS-CoV-2 omicron BA.5 and XBB variants have increased neurotropic potential over BA.1 in K18-hACE2 mice and human brain organoids. Frontiers in Microbiology, 14 1320856, 1-18. doi: 10.3389/fmicb.2023.1320856

Petrone, Mary E., Parry, Rhys, Mifsud, Jonathon C. O., Van Brussel, Kate, Vorhees, Ian, Richards, Zoe T. and Holmes, Edward C. (2023). Evidence for an ancient aquatic origin of the RNA viral order Articulavirales. Proceedings of the National Academy of Sciences, 120 (45) e2310529120, 1-10. doi: 10.1073/pnas.2310529120

Cheng, Rong, Li, Dan, Duan, De-yong, Parry, Rhys, Cheng, Tian-yin and Liu, Lei (2023). Egg protein profile and dynamics during embryogenesis in Haemaphysalis flava ticks. Ticks and Tick-borne Diseases, 14 (4) 102180, 1-9. doi: 10.1016/j.ttbdis.2023.102180

Edwards, Mark R., Forbes, Gordon, Walker, Neil, Morton, Dion G., Mythen, Monty G., Murray, Dave, Anderson, Iain, Mihaylova, Borislava, Thomson, Ann, Taylor, Matt, Hollyman, Marianne, Phillips, Rachel, Young, Keith, Kahan, Brennan C., Pearse, Rupert M., Grocott, Michael P. W., Skubala, Alexandra, Tapley, Patrick, Kellett, Suzanne, Bolger, Clare, Burnish, Rachel, Collings, Nikki, Cumpstey, Andrew, Wong, Hannah, Rehnberg, Vic, Lees, Jessica, Salmon, Karen, Wee, Naomi, Harrison, Sarah ... Brennan, Christopher (2023). Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery. Trials, 24 (1) 313, 1-16. doi: 10.1186/s13063-023-07275-3

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. Journal of Virology, 97 (5) e0045123, 1-3. doi: 10.1128/jvi.00451-23

Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022

Bamford, Connor G. G., de Souza, William M., Parry, Rhys and Gifford, Robert J. (2022). Comparative analysis of genome-encoded viral sequences reveals the evolutionary history of flavivirids (family Flaviviridae). Virus Evolution, 8 (2) veac085, veac085. doi: 10.1093/ve/veac085

Torres, Francisco J., Parry, Rhys, Hugo, Leon E., Slonchak, Andrii, Newton, Natalee D., Vet, Laura J., Modhiran, Naphak, Pullinger, Brody, Wang, Xiaohui, Potter, James, Winterford, Clay, Hobson-Peters, Jody, Hall, Roy A. and Khromykh, Alexander A. (2022). Reporter flaviviruses as tools to demonstrate homologous and heterologous superinfection exclusion. Viruses, 14 (7) 1501, 1501. doi: 10.3390/v14071501

Kouli, O., Murray, V., Bhatia, S., Cambridge, W. A., Kawka, M., Shafi, S., Knight, S. R., Kamarajah, S. K., McLean, K. A., Glasbey, J. C., Khaw, R. A., Ahmed, W., Akhbari, M., Baker, D., Borakati, A., Mills, E., Thavayogan, R., Yasin, I., Raubenheimer, K., Ridley, W., Sarrami, M., Zhang, G., Egoroff, N., Pockney, P., Richards, T., Bhangu, A., Creagh-Brown, B., Edwards, M., Harrison, E. M. ... Wischhusen, S. (2022). Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study. The Lancet Digital Health, 4 (7), e520-e531. doi: 10.1016/S2589-7500(22)00069-3

Slonchak, Andrii, Parry, Rhys, Pullinger, Brody, Sng, Julian D. J., Wang, Xiaohui, Buck, Teresa F., Torres, Francisco J., Harrison, Jessica J., Colmant, Agathe M. G., Hobson-Peters, Jody, Hall, Roy A., Tuplin, Andrew and Khromykh, Alexander A. (2022). Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution. Nature Communications, 13 (1) 1279, 1-16. doi: 10.1038/s41467-022-28977-3

Gestuveo, Rommel J., Parry, Rhys, Dickson, Laura B., Lequime, Sebastian, Sreenu, Vattipally B., Arnold, Matthew J., Khromykh, Alexander A., Schnettler, Esther, Lambrechts, Louis, Varjak, Margus and Kohl, Alain (2022). Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs. PLOS Pathogens, 18 (1) e1010202, 1-29. doi: 10.1371/journal.ppat.1010202

Parry, Rhys, de Malmanche, Henry and Asgari, Sassan (2021). Persistent Spodoptera frugiperda rhabdovirus infection in Sf9 cells is not restricted by Wolbachia wMelPop-CLA and wAlbB strains and is targeted by the RNAi machinery. Virology, 563, 82-87. doi: 10.1016/j.virol.2021.08.013

Parry, Rhys, Gifford, Robert J., Lytras, Spyros, Ray, Stuart C. and Coin, Lachlan J. M. (2021). No evidence of SARS-CoV-2 reverse transcription and integration as the origin of chimeric transcripts in patient tissues. Proceedings of the National Academy of Sciences, 118 (33) e2109066118, e2109066118. doi: 10.1073/pnas.2109066118

Parry, Rhys, James, Maddie E. and Asgari, Sassan (2021). Uncovering the worldwide diversity and evolution of the virome of the mosquitoes Aedes aegypti and Aedes albopictus. Microorganisms, 9 (8) 1653, 1653. doi: 10.3390/microorganisms9081653

Jansen van Vuren, Petrus , Parry, Rhys, Khromykh, Alexander A. and Paweska, Janusz T. (2021). A 1958 isolate of Kedougou Virus (KEDV) from Ndumu, South Africa, expands the geographic and temporal range of KEDV in Africa. Viruses, 13 (7) 1368, 1368. doi: 10.3390/v13071368

Perdomo, Hugo D., Hussain, Mazhar, Parry, Rhys, Etebari, Kayvan, Hedges, Lauren M., Zhang, Guangmei, Schulz, Benjamin L. and Asgari, Sassan (2021). Human blood microRNA hsa-miR-21-5p induces vitellogenin in the mosquito Aedes aegypti. Communications Biology, 4 (1) 856, 856. doi: 10.1038/s42003-021-02385-7

Etebari, Kayvan, Parry, Rhys, Beltran, Marie Joy B. and Furlong, Michael J. (2020). Transcription profile and genomic variation of Oryctes rhinoceros nudivirus (OrNV) in Coconut Rhinoceros Beetle. Journal of Virology, 94 (22) e01097-20, 1-18. doi: 10.1128/jvi.01097-20

Rawle, Daniel J., Nguyen, Wilson, Dumenil, Troy, Parry, Rhys, Warrilow, David, Tang, Bing, Le, Thuy T., Slonchak, Andrii, Khromykh, Alexander A., Lutzky, Viviana P., Yan, Kexin and Suhrbier, Andreas (2020). Sequencing of historical isolates, k‐mer mining and high serological cross‐reactivity with Ross River virus argue against the presence of Getah virus in Australia. Pathogens, 9 (10) 848, 1-17. doi: 10.3390/pathogens9100848

Parry, Rhys, Wille, Michelle, Turnbull, Olivia M. H., Geoghegan, Jemma L. and Holmes, Edward C. (2020). Divergent influenza-like viruses of amphibians and fish support an ancient evolutionary association. Viruses, 12 (9) 1042, 1042. doi: 10.3390/v12091042

Pollock, David D., Castoe, Todd A., Perry, Blair W., Lytras, Spyros, Wade, Kristen J., Robertson, David L., Holmes, Edward C., Boni, Maciej F., Kosakovsky Pond, Sergei L., Parry, Rhys, Carlton, Elizabeth J., Wood, James L. N., Pennings, Pleuni S. and Goldstein, Richard A. (2020). Viral CpG deficiency provides no evidence that dogs were intermediate hosts for SARS-CoV-2. Molecular Biology and Evolution, 37 (9), 2706-2710. doi: 10.1093/molbev/msaa178

Parry, Rhys, Naccache, Fanny, Ndiaye, El Hadji, Fall, Gamou, Castelli, Ilaria, Lühken, Renke, Medlock, Jolyon, Cull, Benjamin, Hesson, Jenny C., Montarsi, Fabrizio, Failloux, Anna-Bella, Kohl, Alain, Schnettler, Esther, Diallo, Mawlouth, Asgari, Sassan, Dietrich, Isabelle and Becker, Stefanie C. (2020). Identification and RNAi profile of a novel iflavirus infecting Senegalese Aedes vexans arabiensis mosquitoes. Viruses, 12 (4) 440, 440. doi: 10.3390/v12040440

Madhav, Mukund, Parry, Rhys, Morgan, Jess A. T., James, Peter and Asgari, Sassan (2020). Wolbachia endosymbiont of the horn fly Haematobia irritans irritans: a supergroup A strain with multiple horizontally acquired cytoplasmic incompatibility genes. Applied and Environmental Microbiology, 86 (6) e02589. doi: 10.1128/aem.02589-19

Bishop, Cameron, Parry, Rhys and Asgari, Sassan (2019). Effect of Wolbachia wAlbB on a positive-sense RNA negev-like virus: a novel virus persistently infecting Aedes albopictus mosquitoes and cells. Journal of General Virology, 101 (2) 001361, 216-225. doi: 10.1099/jgv.0.001361

Parry, Rhys and Asgari, Sassan (2019). Discovery of novel crustacean and cephalopod flaviviruses: insights into evolution and circulation of flaviviruses between marine invertebrate and vertebrate hosts. Journal of Virology, 93 (14) e00432. doi: 10.1128/JVI.00432-19

Parry, Rhys, Bishop, Cameron, De Hayr, Lachlan and Asgari, Sassan (2019). Density-dependent enhanced replication of a densovirus in Wolbachia-infected Aedes cells is associated with production of piRNAs and higher virus-derived siRNAs. Virology, 528, 89-100. doi: 10.1016/j.virol.2018.12.006

Parry, Rhys and Asgari, Sassan (2018). Aedes Anphevirus: an insect-specific virus distributed worldwide in Aedes aegypti mosquitoes that has complex interplays with Wolbachia and dengue virus infection in cells. Journal of Virology, 92 (17) e00224-18, JVI.00224-18. doi: 10.1128/JVI.00224-18

Zakrzewski, Martha, Rašić, Gordana, Darbro, Jonathan, Krause, Lutz, Poo, Yee S., Filipović, Igor, Parry, Rhys, Asgari, Sassan, Devine, Greg and Suhrbier, Andreas (2018). Mapping the virome in wild-caught Aedes aegypti from Cairns and Bangkok. Scientific Reports, 8 (1) 4690, 4690. doi: 10.1038/s41598-018-22945-y

Asad, Sultan, Parry, Rhys and Asgari, Sassan (2018). Upregulation of Aedes aegypti Vago1 by Wolbachia and its effect on dengue virus replication. Insect Biochemistry and Molecular Biology, 92, 45-52. doi: 10.1016/j.ibmb.2017.11.008

Thesis

Parry, Rhys (2021). Endosymbionts and viromes: interplays between Wolbachia pipientis and the virome of Aedes mosquitoes. PhD Thesis, School of Biological Sciences, The University of Queensland. doi: 10.14264/abcdf38