Associate Professor Marloes Nitert Dekker
Primary research interest
Metabolism and microbiome in pregnancy
About me
I have a MSc in Medical Biology from the University of Amsterdam, The Netherlands. I moved to Sweden to study the role of Insulin and IGF-1 receptors in endothelial cells obtaining a Licentiate Degree in Medical Cell Biology at Linköping University, Sweden in 2005. I pursued my PhD at Lund University, Sweden in Molecular Metabolism of the pancreatic beta cells (2007).
In my first post-doctoral scholarship funded by the Nordic Centre of Excellence in Disease Genetics and the Swedish Society for Medical Research, I investigated the role of epigentics in the pathogenesis of type 2 diabetes. I then moved to Australia in 2011 to pursue research into metabolism in pregnancy. I am the key scientist of the SPRING RCT team which aims to prevent gestational diabetes mellitus in overweight and obese pregnant women with probiotics.
I joined the School of Chemistry and Molecular Biosciences as a Senior Lecturer in Metabolism and to continue my research into metabolism and the microbiome in pregnancy.
Research focus and collaborations
The focus of the Metabolism and Microbiome in Pregnancy lab is on understanding the role of the microbiome in shaping metabolic changes in pregnancy and pregnancy complications such as gestational diabetes mellitus and preeclampsia. The rate of pregnancy complications is increasing in line with the rise in overweight and obesity in women of childbearing age. Recently, it has become clear that the microbiome i.e. the composite of microorganisms present on an organism, is an important regulator of many physiological processes including metabolism and immunity. The lab uses samples obtained from clinical studies to investigate the mechanisms by which the microbiome regulates metabolism in pregnancy.
The lab has a close collaboration with clinician-scientists at the Royal Brisbane and Women's Hospital: Professor Leonie Callaway and the Mater Mothers' Hospital: Professor David McIntyre and Associate Professor Shelley Wilkinson and with Associate Professor Helen Barrett at the University of Sydney. For our lipid studies, we collaborate with Professor Barbara Meyer at the University of Wollongong and Dr Dilys Freeman at the University of Glasgow, UK. We collaborate with Professor William Hague at the University of Adelaide for our studies on the role of bile acid metabolism and the gut microbiome in women with or at high risk for Intrahepatic Cholestasis of Pregnancy.
Our research group is part of the Queensland Perinatal Consortium (QPACT), a collaboration between research groups interested in perinatal research within South-East Queensland.
Funded projects
- 2023 – $50,000 in support from Ferring Pharmaceuticals for investigating changes in the microbiome of women with intrahepatic cholestasis of pregnancy after treatment with ursodeoxycholic acid or rifampicin.
- 2022 – $4,500,000 in support from Meat and Livestock Australia for project on Low Emission Saliva Test for Ruminants (LESTR). Lead for Microbiome in Pregnancy analysis.
- 2021 – $60,000 in support from the Diabetes Australia Research Programme for investigating hyperglycaemia in women pregnant after bariatric surgery.
- 2021 – $20,000 in support from UQ Faculty of Science COVID Research Recovery Fund.
- 2020 – $29,327 in project support from the CRE Digestive Health Pilot grant scheme for study of high intensity interval training (HIIT) on human gut microbiome functional diversity, inflammation and body composition in colorectal cancer survivors.
- 2019 – $60,000 in support from the RACP for study of the effects of preeclampsia on gut permeability?
- 2018 – $25,000 in project support from the IHBI QIMRB Seed funding scheme for study of allergy-associated changes in the functional capacity of the maternal and infant microbial community.
- 2018 – $22,000 in support from the UQ Faculty of Science for the organization of a Nature Writing Masterclass for Early and Mid Career Researchers.
- 2018 – $39,936 in project support from the Royal Brisbane and Women’s Foundation for study of the role of probiotics in the prevention of allergic disease in children.
- 2017 – $42,876 in project support from the Royal Brisbane and Women’s Foundation for study of antibiotics in pregnancy: unintended effects on the microbiome, maternal metabolism and infant body composition.
- 2017 – $42,876 in project support from the Royal Brisbane and Women’s Foundation for study of the long-term consequences of altered neonatal adiposity.
- 2017 – $40,000 in project support from the UQ Early Career Researcher grants for study of the role the gut microbiome in the regulation of blood pressure in overweight and obese pregnant women.
- 2017 – $276,265 from the UQ Major Equipment Infrastructure grants for upgrades of preparative centrifuge and ultracentrifuge systems and rotors at the School of Chemistry and Molecular Biosciences as part of a consortium of SCMB researchers.
- 2017 – $65,439 in project support from the Diabetes Australia Research Programme for study of the linkages in the maternal and infant microbiome: effects of GDM or probiotics?
- 2017-2019 - $487,273 AUD in project support from NHMRC for project Trophoblast cell-cell fusion in preeclampsia.
- 2016 – $40,000 in project support from the Royal Brisbane and Women’s Hospital Foundation for study of the prevalence of antimicrobial resistance genes in the gut microbiome of overweight and obese pregnant women.
- 2016 – $40,000 in project support from the Royal Brisbane and Women’s Hospital Foundation for study of ketone production after a carbohydrate restricted meal in women with GDM.
- 2016 – $36,740 in project support from the Royal Brisbane and Women’s Hospital Foundation for study of postprandial triglycerides in diabetes in pregnancy: a pilot study.
- 2015 – $40,000 in project support from the Royal Brisbane and Women’ Hospital Foundation for study of the prevalence of antimicrobial resistance genes in the gut microbiome of overweight and obese pregnant women.
- 2015 – $40,000 in project support from the Royal Brisbane and Women’ Hospital Foundation for study of ketone production after a carbohydrate-restricted meal in women with GDM.
- 2015 – $36,740 in project support from the Royal Brisbane and Women’ Hospital Foundation for study of postprandial triglycerides in diabetes in pregnancy: a pilot study.
- 2014 – $40,000 in project support from the Royal Brisbane and Women’ Hospital Foundation for study of the comparison of the microbiomes of the gut, oral cavity and placenta in mother and baby dyads.
- 2014 – $40 000 in project support from the Royal Brisbane and Women’ Hospital Foundation for study of periconception weight loss and the epigenetic regulation of stress and growth in the infant.
- 2014 – $78,000 AUD in project support from the Queensland Health Strategic Health Initiatives for Longitudinal effects of probiotic supplementation during pregnancy on the body composition and growth of infants.
- 2014 – $25,000 AUD in project support from the QCMR and QUT Collaborative Seeding Grants Scheme for study of environmental pollutants—transfer from mother to fetus.
- 2013 – $40,000 AUD in project support from the Royal Brisbane and Women’s Hospital Foundation for study of metabolic toxins and placental function.
- 2012 – $40,000 AUD in project support from the Royal Brisbane and Women’s Hospital Foundation for study of the role of the gut microbiome in the development of gestational diabetes.
- 2012 – $6,600 AUD in project support from Australian Diabetes in Pregnancy Society – Novo Nordisk Scientific Research Grant for project Gene expression and DNA methylation of diabetes-associated genes in the placenta and offspring neonatal buccal cells from pregnancies complicated by gestational diabetes mellitus.
- 2012 – $31,000 AUD in project support from the Royal Brisbane and Women’s Hospital Foundation for study of the role of maternal prepregnancy weight loss on the neonatal stress response.
- 2012 – $13 000 AUD in project support from the Royal Brisbane and Women’s Hospital Foundation for the measurement of maternal triglyceride metabolism in the third trimester of pregnancy.
- 2012-2015 - $828,000 AUD in project support from NHMRC for project Priobiotics to prevent gestational diabetes.
- 2011 - $40,000 AUD in project support from RBWH foundation for project Impact of metformin treatment for gestational diabetes: A prospective observational study.
- 2011 - $39,000 AUD in project support from Pfizer Australia for project Placental expression of lipoprotein lipase, endothelial lipase and hormone-sensitive lipase in pregnancies complicated by pre-eclampsia or eclampsia or intrauterine growth retardation.
- 2010 - $10,000 in project support from Tore Nilssons stiftelse för medicinsk forskning.
- 2009 - $10,000 AUD in project support from Fredrik och Ingrid Thurings stiftelse för medicinsk forskning.
- 2009 - $11,000 AUD in project support from Tore Nilssons stiftelse för medicinsk forskning.
- 2009 - $10,000 AUD in project support from the Nilsson-Ehle donations.
Teaching interests
I teach into a variety of courses, focusing on metabolism (BIOC3006, NEUR3001, BIOM3020), microbiome (MICR3004, BIOL1007) and developmental genetics (BIOC3003, BIOL1007, DEVB2000) for students in the Bachelor of (Advanced) Science, Bachelor of Biomedical Science, Bachelor of Exercise and Nutrition Science, Bachelor of Health Science, Bachelor of Physiotherapy and the Doctor of Medicine programs. I am a Senior Fellow of the Higher Education Academy.
BIOC3006 - Biochemistry of Metabolism in Health & Disease
NEUR3001 - Molecular & Cellular Neuroscience
BIOM3020 - Integrated Endocrinology
MICR3004 - Microbial Genomics
BIOL1007 - Molecular & Cellular Biology for Physiotherapists
DEVB2000 - Stem Cells, Development and Developmental Disorders
BIOC3003 - Human Molecular Genetics in Health & Disease
Achievements and awards
- 2023 – Award for Outstanding Contribution of Education from the UQ School of Chemistry and Molecular Biosciences
- 2022 – Metro North Research Excellence Awards category Clinical Research Award
- 2021 – Senior Fellow of the Higher Education Academy
- 2020 – Award for Outstanding Contribution to Equity, Diversity and Inclusion from the UQ School of Chemistry and Molecular Biosciences for the Women in Science Podcast series.
- 2017 – Metro North Research Excellence Awards category Complex Health Challenges Research Award for the Obstetric Medicine research team
- 2016 – Graz-Clock Award for best overall oral presentation, Australasian Diabetes in Pregnancy Society
- 2016 – Chair Program Organising Committee ADIPS annual scientific meeting, Gold Coast
- 2014 – current Council Member Society of Obstetric Medicine Australia and New Zealand
Researcher biography
Dr Marloes Dekker Nitert is an Associate Professor at The University of Queensland. Marloes is a biomedical researcher with a PhD from Lund University in Sweden. Her research focuses on the role of metabolism in complications of pregnancy. She currently heads a laboratory research group at the School of Chemistry and Molecular Biosciences studying the role of metabolism in pregnancy complications and especially how the gut microbiome contributes to a healthy pregnancy and to pregnancy complications. Marloes works closely together with clinician-scientists and clinicians at the Royal Brisbane and Women's Hospital and the Mater Mothers' Hospital to do her translational research. Marloes is a board member of the Australian Society for Medical Research and a past Council member of the Society of Obstetric Medicine Australia and New Zealand.