Publications
Journal Articles
Tse, Edwin G., Houston, Sevan D., Williams, Craig M., Savage, G. Paul, Rendina, Louis M., Hallyburton, Irene, Anderson, Mark, Sharma, Raman, Walker, Gregory S., Obach, R. Scott and Todd, Matthew H. (2020). Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials. Journal of Medicinal Chemistry, 63 (20) acs.jmedchem.0c00746, 11585-11601. doi: 10.1021/acs.jmedchem.0c00746
Dallaston, Madeleine A., Houston, Sevan D. and Williams, Craig M. (2020). Cubane, Bicyclo[1.1.1]pentane and Bicyclo[2.2.2]octane: Impact and Thermal Sensitiveness of Carboxyl-, Hydroxymethyl- and Iodo-substituents. Chemistry - A European Journal, 26 (52) chem.202001658, 11966-11970. doi: 10.1002/chem.202001658
Tan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522
Houston, Sevan D., Fahrenhorst-Jones, Tyler, Xing, Hui, Chalmers, Benjamin A., Sykes, Melissa L., Stok, Jeanette E., Farfan Soto, Clementina, Burns, Jed M., Bernhardt, Paul V., De Voss, James J., Boyle, Glen M., Smith, Maree T., Tsanaktsidis, John, Savage, G. Paul, Avery, Vicky M. and Williams, Craig M. (2019). The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement. Organic and Biomolecular Chemistry, 17 (28), 6790-6798. doi: 10.1039/c9ob01238a
Houston, Sevan D., Xing, Hui, Bernhardt, Paul V., Vanden Berg, Timothy J., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2019). Cyclooctatetraenes through valence isomerization of cubanes: scope and limitations. Chemistry: A European Journal, 25 (11), 2735-2739. doi: 10.1002/chem.201805124
Houston, Sevan D., Chalmers, Benjamin A., Savage, G. Paul and Williams, Craig M. (2019). Enantioselective synthesis of (R)-2-cubylglycine including unprecedented rhodium mediated C–H insertion of cubane. Organic & Biomolecular Chemistry, 17 (5), 1067-1070. doi: 10.1039/c8ob02959h
Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675