Professor Benjamin Schulz
BSc Biochemistry (UQ), BEng Chemical (UQ), Dr. sc. Microbiology (ETH Zurich)
Professor
School of Chemistry and Molecular Biosciences
+61 7 336 54875
Chemistry Building (68), Room 450
Primary research interest
Molecular systems glycobiology
About me
I am a Professor in Biochemistry, with research interests in molecular systems biology and engineering protein post-translational modifications. I graduated with a degree in Chemical Engineering and Science from The University of Queensland, after which I joined Proteome Systems, an Australian biotechnology company. I moved to the ETH Zurich in Switzerland for my doctoral studies, and then returned to the School of Chemistry & Molecular Biosciences as a post-doctoral research fellow, and now teaching and research academic.
Research focus and collaborations
The research in my group focuses on the mechanisms, biological roles and applications in biotechnology of glycosylation, the most abundant and complex post-translational modification of proteins. Glycosylation is important in biological processes such as viral infection, cancer, and development. This is because glycosylation is essential in biological activities as diverse as protein folding, fine-tuning protein enzymatic activity and determining protein-protein interactions. Half of all proteins are glycosylated, and a single protein can be modified by hundreds of different sugar moieties.
The diversity of glycoproteins therefore requires that we take a systems biology approach in our research. All our projects use a core set of methods in molecular biology, genetic manipulation, protein biochemistry, protein analysis and mass spectrometry. We aim to understand the mechanisms controlling glycosylation in these various systems to develop diagnostics, therapies, vaccines and applications in biotechnology.
We also use our systems biology approaches in diverse national and international collaborations in biomedicine, infectious disease, agriculture, and beverages.
Glycosylation in health and disease
Altered glycosylation is associated with cancer and infection. We aim to understand the mechanisms controlling this process using in vitro protein biochemistry, a yeast model system and human cells, to determine how it affects glycoprotein function.
Viral glycobiology
Glycosylation shields viruses from the immune response and is critical for many of the functions of viral proteins. This is especially important for the respiratory pathogens Influenza virus and SARS-CoV-2. We aim to understand the mechanisms controlling these processes using cell-based infection systems, protein structural and biochemical analyses, mass spectrometry glycoproteomics, and bioinformatics to determine their impact on viral biology and vaccine design.
Engineering glycoprotein biopharmaceuticals
Many important biopharmaceuticals are glycoproteins, such as monoclonal antibodies and vaccines. The glycosylation and other post-translational modifications of these proteins are critical for their function, but recombinant proteins produced from mammalian cell culture are often different to the native proteins. We use mass spectrometry for detailed structural analysis of biopharmaceuticals, and cell-line and protein engineering to improve their quality.
Beer, wine, and yeast
Beer brewing and wine making are perhaps the most ancient biotechnologies. We use modern analytical techniques to investigate and improve these complex and important processes, and to investigate the metabolic diversity of wild yeasts.
Group members
- Ms Joy Seit, PhD student
- Mr Daniel Ellis, PhD student
- Ms Shulei Liu, PhD student
- Mr Kyle Macauslane, PhD student
Funded projects
- NHMRC e-ASIA Grant 2023-2025.
Gut leak and microbiome contribution to severe dengue disease. - ARC Linkage Grant 2022-2026.
Applications-oriented elucidation of germination triggers for Emu Bush seed. - NHMRC Ideas Grant 2020-2022.
The dynamic glycoproteome in influenza infection.
Teaching interests
- BIOC2000 Biochemistry and Molecular Biology
- BIOC3000 Structural & Synthetic Biology
- BIOC7040 Advanced Protein & Nucleic Acids
- BIOC 2001 Foundations of Biophysics
- SCIE1200 Introduction to Science Research
- SCIE2020 CSI UQ: Introduction to Forensic Science
- VETS1003 Digestion, Metabolism & Nutrition
Achievements and awards
- SCMB HDR Supervision Excellence Award 2022
- UQ Foundation Research Excellence Award 2017
- ASBMB Bioplatforms Australia Award 2015
- ASBMB Eppendorf Edman Award 2015
Featured publications
- Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L., and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology 34 (2) cwad097 1-13. https://doi.org/10.1093/glycob/cwad097
- Kerr, Edward D., Fox, Glen P., and Schulz, Benjamin L. (2023). Proteomics and metabolomics reveal that an abundant α-glucosidase drives sorghum fermentability for beer brewing. Journal of Proteome Research 22 (11) 3596-3606. https://doi.org/10.1021/acs.jproteome.3c00436
- Kerr, Edward D., Caboche, Christopher H., Pegg, Cassandra L., Phung, Toan K., Gonzalez Viejo, Claudia, Fuentes, Sigfredo, Howes, Mark T., Howell, Kate and Schulz, Benjamin L. (2021).The post-translational modification landscape of commercial beers. Scientific Reports, 11 (1) 15890, 15890. doi: 10.1038/s41598-021-95036-0
- Zacchi, Lucia F., Roche-Recinos, Dinora, Pegg, Cassandra L., Phung, Toan K., Napoli, Mark, Aitken, Campbell, Sandford, Vanessa, Mahler, Stephen M., Lee, Yih Yean, Schulz, Benjamin L. and Howard, Christopher B. (2021).Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product. Communications Biology, 4 (1) 390, 390. doi: 10.1038/s42003-021-01903-x
- Pegg CL, Phung TK, Caboche CH, Niamsuphap S, Bern M, Howell K, Schulz BL (2020) Quantitative Data-Independent Acquisition Glycoproteomics of Sparkling Wine. Mol Cell Proteomics. 2020 Dec 21;20:100020. doi: 10.1074/mcp.RA120.002181.
- Stevens KLP, Black AL, Wells KM, Yeo KYB, Steuart RFL, Stirling CJ, Schulz BL, Mousley CJ. Diminished Ost3-dependent N-glycosylation of the BiP nucleotide exchange factor Sil1 is an adaptive response to reductive ER stress. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12489-12494. doi: 10.1073/pnas.1705641114.
Researcher biography
I graduated with a degree in Chemical Engineering and Science in 2000 from The University of Queensland, after which I joined Proteome Systems, an Australian biotechnology company. In 2004 I moved to the ETH Zurich in Switzerland for my doctoral studies. I joined the School of Chemistry & Molecular Biosciences as a University of Queensland Postdoctoral Research Fellow in 2008 and NHMRC Career Development Fellow in 2012. I am now Associate Professor in Biochemistry.
Book Chapters
Kerr, Edward D., Fox, Glen P. and Schulz, Benjamin L. (2021). Grass to glass: better beer through proteomics. Comprehensive Foodomics. (pp. 407-416) Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-08-100596-5.22869-2
Schulz, Benjamin L. (2019). Sample preparation for proteomic analysis of Neisseria meningitidis. Neisseria meningitidis: methods and protocols. (pp. 105-112) New York, NY, United States: Humana. doi: 10.1007/978-1-4939-9202-7_7
Zacchi, Lucía F. and Schulz, Benjamin L. (2019). Data-independent acquisition for yeast glycoproteomics. Yeast systems biology. (pp. 191-202) New York, NY USA: Humana Press. doi: 10.1007/978-1-4939-9736-7_11
Schulz, Benjamin Luke (2012). Beyond the sequon: sites of N-Glycosylation. Glycosylation. (pp. 21-40) edited by Stefana Petrescu. Rijeka, Croatia: InTech. doi: 10.5772/50260
Journal Articles
Xiang, Enmao, Vaquette, Cedryck, Liu, Shulei, Raveendran, Nimal, Schulz, Benjamin L., Nowwarote, Nunthawan, Dargusch, Matthew, Abdal-hay, Abdalla, Fournier, Benjamin P. J. and Ivanovski, Saso (2024). Biomimetic surface nanoengineering of biodegradable Zn-based orthopedic implants for enhanced biocompatibility and immunomodulation. Advanced Functional Materials, 34 (51) 2410033. doi: 10.1002/adfm.202410033
Macauslane, Kyle L., Pegg, Cassandra L., Short, Kirsty R. and Schulz, Benjamin L. (2024). Modulation of endoplasmic reticulum stress response pathways by respiratory viruses. Critical Reviews in Microbiology, 50 (5), 750-768. doi: 10.1080/1040841x.2023.2274840
Sinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z
Macauslane, Kyle L., Pegg, Cassandra L., Nouwens, Amanda S., Kerr, Edward D., Seitanidou, Joy and Schulz, Benjamin L. (2024). Electron-Activated Dissociation and Collision-Induced Dissociation Glycopeptide Fragmentation for Improved Glycoproteomics. Analytical Chemistry, 96 (27), 10986-10994. doi: 10.1021/acs.analchem.4c01450
Busby, Jason N., Trevelyan, Sarah, Pegg, Cassandra L., Kerr, Edward D., Schulz, Benjamin L., Chassagnon, Irene, Landsberg, Michael J., Weston, Mitchell K., Hurst, Mark R. H. and Lott, J. Shaun (2024). The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both shell and cargo. IUCrJ, 11 (3), 299-308. doi: 10.1107/s2052252524001969
Stupar, Miljan, Tan, Lendl, Kerr, Edward D., De Voss, Christopher J., Forde, Brian M., Schulz, Benjamin L. and West, Nicholas P. (2024). TcrXY is an acid-sensing two-component transcriptional regulator of Mycobacterium tuberculosis required for persistent infection. Nature Communications, 15 (1) 1615, 1-14. doi: 10.1038/s41467-024-45343-7
Yu, Chendi K., Stephenson, Christina J., Villamor, Tristan C., Dyba, Taylor G., Schulz, Benjamin L. and Fraser, James A. (2023). SAGA complex subunit Hfi1 is important in the stress response and pathogenesis of Cryptococcus neoformans. Journal of Fungi, 9 (12) 1198, 1-16. doi: 10.3390/jof9121198
Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L. and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology, 34 (2) cwad097, 1-13. doi: 10.1093/glycob/cwad097
Hakme, Elena, Kallehauge Nielsen, Ida, Fermina Madsen, Jennifer, Storkehave, Lasse Munch, Skjold Elmelund Pedersen, Mette, Schulz, Benjamin Luke, Poulsen, Mette Erecius, Hobley, Timothy John and Duedahl-Olesen, Lene (2023). Fate of pesticide residues in beer and its by-products. Food Additives and Contaminants: Part A, 41 (1), 45-59. doi: 10.1080/19440049.2023.2282557
Kerr, Edward D., Fox, Glen P. and Schulz, Benjamin L. (2023). Proteomics and metabolomics reveal that an abundant α-glucosidase drives sorghum fermentability for beer brewing. Journal of Proteome Research, 22 (11), 3596-3606. doi: 10.1021/acs.jproteome.3c00436
Forknall, Clayton R., Verbyla, Arūnas P., Nazarathy, Yoni, Yousif, Adel, Osama, Sarah, Jones, Shirley H., Kerr, Edward, Schulz, Benjamin L., Fox, Glen P. and Kelly, Alison M. (2023). Covariance clustering: modelling covariance in designed experiments when the number of variables is greater than experimental units. Journal of Agricultural, Biological and Environmental Statistics, 29 (2), 232-256. doi: 10.1007/s13253-023-00574-x
Jen, Freda E.-C., Abrahams, Jodie L., Schulz, Benjamin L., Lamelas, Araceli, Pluschke, Gerd and Jennings, Michael P. (2023). High-frequency changes in pilin glycosylation patterns during Neisseria meningitidis Serogroup a Meningitis Outbreaks in the African meningitis belt. ACS Infectious Diseases, 9 (8), 1451-1457. doi: 10.1021/acsinfecdis.3c00149
Isaacs, Ariel, Low, Yu Shang, Macauslane, Kyle L., Seitanidou, Joy, Pegg, Cassandra L., Cheung, Stacey T. M., Liang, Benjamin, Scott, Connor A. P., Landsberg, Michael J., Schulz, Benjamin L., Chappell, Keith J., Modhiran, Naphak and Watterson, Daniel (2023). Structure and antigenicity of divergent Henipavirus fusion glycoproteins. Nature Communications, 14 (1) 3577, 1-10. doi: 10.1038/s41467-023-39278-8
Raza, Ali, Schulz, Benjamin L., Nouwens, Amanda, Naseem, Muhammad Noman, Kamran, Muhammad, Mantilla Valdivieso, Emily F., Kerr, Edward D., Constantinoiu, Constantin, Jonsson, Nicholas N., James, Peter and Tabor, Ala E. (2023). Application of quantitative proteomics to discover biomarkers for tick resistance in cattle. Frontiers in Immunology, 14 1091066, 1091066. doi: 10.3389/fimmu.2023.1091066
Pegg, Cassandra L., Schulz, Benjamin L., Neely, Benjamin A., Albery, Gregory F. and Carlson, Colin J. (2023). Glycosylation and the global virome. Molecular Ecology, 32 (1), 37-44. doi: 10.1111/mec.16731
Massel, Karen, Hintzsche, Jessica, Restall, Jemma, Kerr, Edward D., Schulz, Benjamin L. and Godwin, Ian D. (2022). CRISPR-knockout of β-kafirin in sorghum does not recapitulate the grain quality of natural mutants. Planta, 257 (1) 8, 1-14. doi: 10.1007/s00425-022-04038-3
Li, Hai-Teng, Kerr, Edward D., Schulz, Benjamin L., Gidley, Michael J. and Dhital, Sushil (2022). Pasting properties of high-amylose wheat in conventional and high-temperature Rapid Visco Analyzer: molecular contribution of starch and gluten proteins. Food Hydrocolloids, 131 107840, 1-10. doi: 10.1016/j.foodhyd.2022.107840
Ellis, Daniel J., Kerr, Edward D., Schenk, Gerhard and Schulz, Benjamin L. (2022). Metabolomics of non-saccharomyces yeasts in fermented beverages. Beverages, 8 (3) 41, 1-14. doi: 10.3390/beverages8030041
Liu, Shulei, Kerr, Edward D., Pegg, Cassandra L. and Schulz, Benjamin L. (2022). Proteomics and glycoproteomics of beer and wine. Proteomics, 22 (15-16) 2100329, 1-11. doi: 10.1002/pmic.202100329
Beauglehole, Aiden C, Roche Recinos, Dinora, Pegg, Cassandra L, Lee, Yih Yean, Turnbull, Victor, Herrmann, Susann, Marcellin, Esteban, Howard, Christopher B and Schulz, Benjamin L (2022). Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering. Critical Reviews in Biotechnology, 43 (3), 1-19. doi: 10.1080/07388551.2022.2036691
Erpf, Paige E., Chua, Sheena M.H., Phung, Toan K., Kerr, Edward D., Rothnagel, Joseph A., Schulz, Benjamin L. and Fraser, James A. (2022). Identification and characterisation of sPEPs in Cryptococcus neoformans. Fungal Genetics and Biology, 160 103688, 103688. doi: 10.1016/j.fgb.2022.103688
O’Brien, Caitlin A., Huang, Bixing, Warrilow, David, Hazlewood, Jessamine E., Bielefeldt-Ohmann, Helle, Hall-Mendelin, Sonja, Pegg, Cassandra L., Harrison, Jessica J., Paramitha, Devina, Newton, Natalee D., Schulz, Benjamin L., Suhrbier, Andreas, Hobson-Peters, Jody and Hall, Roy A. (2022). Extended characterisation of five archival tick-borne viruses provides insights for virus discovery in Australian ticks. Parasites and Vectors, 15 (1) 59, 59. doi: 10.1186/s13071-022-05176-z
Harbison, Aoife M., Fogarty, Carl A., Phung, Toan K., Satheesan, Akash, Schulz, Benjamin L. and Fadda, Elisa (2022). Fine-tuning the spike: role of the nature and topology of the glycan shield in the structure and dynamics of the SARS-CoV-2 S. Chemical Science, 13 (2), 386-395. doi: 10.1039/d1sc04832e
Kawahara, Rebeca, Chernykh, Anastasia, Alagesan, Kathirvel, Bern, Marshall, Cao, Weiqian, Chalkley, Robert J., Cheng, Kai, Choo, Matthew S., Edwards, Nathan, Goldman, Radoslav, Hoffmann, Marcus, Hu, Yingwei, Huang, Yifan, Kim, Jin Young, Kletter, Doron, Liquet, Benoit, Liu, Mingqi, Mechref, Yehia, Meng, Bo, Neelamegham, Sriram, Nguyen-Khuong, Terry, Nilsson, Jonas, Pap, Adam, Park, Gun Wook, Parker, Benjamin L., Pegg, Cassandra L., Penninger, Josef M., Phung, Toan K., Pioch, Markus ... Thaysen-Andersen, Morten (2021). Author correction: community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nature Methods, 19 (1), 130-130. doi: 10.1038/s41592-021-01368-0
Kerr, Edward D., Caboche, Christopher H., Pegg, Cassandra L., Phung, Toan K., Gonzalez Viejo, Claudia, Fuentes, Sigfredo, Howes, Mark T., Howell, Kate and Schulz, Benjamin L. (2021). The post-translational modification landscape of commercial beers. Scientific Reports, 11 (1) 15890, 15890. doi: 10.1038/s41598-021-95036-0
Kawahara, Rebeca, Chernykh, Anastasia, Alagesan, Kathirvel, Bern, Marshall, Cao, Weiqian, Chalkley, Robert J., Cheng, Kai, Choo, Matthew S., Edwards, Nathan, Goldman, Radoslav, Hoffmann, Marcus, Hu, Yingwei, Huang, Yifan, Kim, Jin Young, Kletter, Doron, Liquet, Benoit, Liu, Mingqi, Mechref, Yehia, Meng, Bo, Neelamegham, Sriram, Nguyen-Khuong, Terry, Nilsson, Jonas, Pap, Adam, Park, Gun Wook, Parker, Benjamin L., Pegg, Cassandra L., Penninger, Josef M., Phung, Toan K., Pioch, Markus ... Thaysen-Andersen, Morten (2021). Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nature Methods, 18 (11), 1304-1316. doi: 10.1038/s41592-021-01309-x
Witham, Christopher M., Paxman, Aleshanee L., Baklous, Lamprini, Steuart, Robert F.L., Schulz, Benjamin L. and Mousley, Carl J. (2021). Cancer associated mutations in Sec61γ alter the permeability of the ER translocase. PLoS Genetics, 17 (8) e1009780, e1009780. doi: 10.1371/journal.pgen.1009780
Honer, Jonas, Niemeyer, Katie M., Fercher, Christian, Diez Tissera, Ana L., Jaberolansar, Noushin, Jafrani, Yohaann M. A., Zhou, Chun, Caramelo, Julio J., Shewan, Annette M., Schulz, Benjamin L., Brodsky, Jeffrey L. and Zacchi, Lucía F. (2021). TorsinA folding and N-linked glycosylation are sensitive to redox homeostasis. Biochimica et Biophysica Acta. Molecular Cell Research, 1868 (9) 119073, 119073. doi: 10.1016/j.bbamcr.2021.119073
Liu, Shulei and Schulz, Benjamin L (2021). Biopharmaceutical quality control with mass spectrometry. Bioanalysis, 13 (16), 1275-1291. doi: 10.4155/bio-2021-0123
Perdomo, Hugo D., Hussain, Mazhar, Parry, Rhys, Etebari, Kayvan, Hedges, Lauren M., Zhang, Guangmei, Schulz, Benjamin L. and Asgari, Sassan (2021). Human blood microRNA hsa-miR-21-5p induces vitellogenin in the mosquito Aedes aegypti. Communications Biology, 4 (1) 856, 856. doi: 10.1038/s42003-021-02385-7
Osama, Sarah K., Kerr, Edward D., Yousif, Adel M., Phung, Toan K., Kelly, Alison M., Fox, Glen P. and Schulz, Benjamin L. (2021). Proteomics reveals commitment to germination in barley seeds is marked by loss of stress response proteins and mobilisation of nutrient reservoirs. Journal of Proteomics, 242 104221, 104221. doi: 10.1016/j.jprot.2021.104221
Rubbab, Tehseen, Pegg, Cassandra L., Phung, Toan K., Nouwens, Amanda S., Yeo, K.Y. Benjamin, Zacchi, Lucia F., Muhammad, Amna, Naqvi, S.M. Saqlan and Schulz, Benjamin L. (2021). N-glycosylation on Oryza sativa root germin-like protein 1 is conserved but not required for stability or activity. Biochemical and Biophysical Research Communications, 553, 72-77. doi: 10.1016/j.bbrc.2021.03.024
Raza, Ali, Schulz, Benjamin L., Nouwens, Amanda, Jackson, Lousie A., Piper, Emily K., James, Peter, Jonsson, Nicholas N. and Tabor, Ala E. (2021). Serum proteomes of Santa Gertrudis cattle before and after infestation with Rhipicephalus australis ticks. Parasite Immunology, 43 (7) e12836, e12836. doi: 10.1111/pim.12836
Zacchi, Lucia F., Roche-Recinos, Dinora, Pegg, Cassandra L., Phung, Toan K., Napoli, Mark, Aitken, Campbell, Sandford, Vanessa, Mahler, Stephen M., Lee, Yih Yean, Schulz, Benjamin L. and Howard, Christopher B. (2021). Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product. Communications Biology, 4 (1) 390, 390. doi: 10.1038/s42003-021-01903-x
Kerr, Edward D., Caboche, Christopher H., Josh, Peter and Schulz, Benjamin L. (2021). Benchtop micro-mashing: high-throughput, robust, experimental beer brewing. Scientific Reports, 11 (1) 1480, 1-10. doi: 10.1038/s41598-020-80442-7
Pegg, Cassandra L., Phung, Toan K., Caboche, Christopher H, Niamsuphap, Suchada, Bern, Marshall, Howell, Kate and Schulz, Benjamin L. (2021). Quantitative data independent acquisition glycoproteomics of sparkling wine. Molecular and Cellular Proteomics, 20 100020, 1-12. doi: 10.1074/mcp.ra120.002181
Zhuang, Aowen, Yap, Felicia Y. T., Borg, Danielle J., McCarthy, Domenica, Fotheringham, Amelia, Leung, Sherman, Penfold, Sally A., Sourris, Karly C., Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2021). The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition). Endocrinology, Diabetes and Metabolism, 4 (3) e00278, e00278. doi: 10.1002/edm2.278
MacDonald, Michael A., Nöbel, Matthias, Roche Recinos, Dinora, Martínez, Verónica S., Schulz, Benjamin L., Howard, Christopher B., Baker, Kym, Shave, Evan, Lee, Yih Yean, Marcellin, Esteban, Mahler, Stephen, Nielsen, Lars Keld and Munro, Trent (2021). Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications. Critical Reviews in Biotechnology, 42 (7), 1-17. doi: 10.1080/07388551.2021.1998821
Brouwer, Stephan, Barnett, Timothy C., Ly, Diane, Kasper, Katherine J., De Oliveira, David M. P., Rivera-Hernandez, Tania, Cork, Amanda J., McIntyre, Liam, Jespersen, Magnus G., Richter, Johanna, Schulz, Benjamin L., Dougan, Gordon, Nizet, Victor, Yuen, Kwok-Yung, You, Yuanhai, McCormick, John K., Sanderson-Smith, Martina L., Davies, Mark R. and Walker, Mark J. (2020). Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes. Nature Communications, 11 (1) 5018, 5018. doi: 10.1038/s41467-020-18700-5
Li, Hai-Teng, Sartika, Rakhmi S., Kerr, Edward D., Schulz, Benjamin L., Gidley, Michael J. and Dhital, Sushil (2020). Starch granular protein of high-amylose wheat gives innate resistance to amylolysis. Food Chemistry, 330 127328, 127328. doi: 10.1016/j.foodchem.2020.127328
O’Brien, Caitlin A., Pegg, Cassandra L., Nouwens, Amanda S., Bielefeldt-Ohmann, Helle, Huang, Bixing, Warrilow, David, Harrison, Jessica J., Haniotis, John, Schulz, Benjamin L., Paramitha, Devina, Colmant, Agathe M. G., Newton, Natalee D., Doggett, Stephen L., Watterson, Daniel, Hobson-Peters, Jody and Hall, Roy A. (2020). A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes. Viruses, 12 (9) 1056, 1056. doi: 10.3390/v12091056
Phung, Toan K, Pegg, Cassandra L and Schulz, Benjamin L (2020). GlypNirO: An automated workflow for quantitative N- and O-linked glycoproteomic data analysis. Beilstein Journal of Organic Chemistry, 16 (1), 2127-2135. doi: 10.3762/bjoc.16.180
Zhou, Chun and Schulz, Benjamin L. (2020). Glycopeptide variable window SWATH for improved data independent acquisition glycoprotein analysis. Analytical Biochemistry, 597 113667, 113667. doi: 10.1016/j.ab.2020.113667
Pegg, Cassandra L., Zacchi, Lucia F., Recinos, Dinora Roche, Howard, Christopher B. and Schulz, Benjamin L. (2020). Identification of novel glycosylation events on human serum-derived factor IX. Glycoconjugate Journal, 37 (4), 471-483. doi: 10.1007/s10719-020-09922-2
Gonzalez Viejo, Claudia, Caboche, Christopher H., Kerr, Edward D., Pegg, Cassandra L., Schulz, Benjamin L., Howell, Kate and Fuentes, Sigfredo (2020). Development of a rapid method to assess beer foamability based on relative protein content using RoboBEER and machine learning modeling. Beverages, 6 (2) 28, 28-11. doi: 10.3390/beverages6020028
Pelingon, Ruby, Pegg, Cassandra L., Zacchi, Lucia F., Phung, Toan K., Howard, Christopher B., Xu, Ping, Hardy, Matthew P., Owczarek, Catherine M. and Schulz, Benjamin L. (2020). Glycoproteomic measurement of site-specific polysialylation. Analytical Biochemistry, 596 113625, 113625. doi: 10.1016/j.ab.2020.113625
Wilson, Liam A., Garcia, David, Pedroso, Marcelo Monteiro, Schulz, Benjamin L., Guddat, Luke W. and Schenk, Gerhard (2020). Adaptation of a continuous, calorimetric kinetic assay to study the agmatinase-catalyzed hydrolytic reaction. Analytical Biochemistry, 595 113618, 113618. doi: 10.1016/j.ab.2020.113618
Zalucki, Yaramah M., Jen, Freda E.-C., Pegg, Cassandra L., Nouwens, Amanda S., Schulz, Benjamin L. and Jennings, Michael P. (2020). Evolution for improved secretion and fitness may be the selective pressures leading to the emergence of two NDM alleles. Biochemical and Biophysical Research Communications, 524 (3), 555-560. doi: 10.1016/j.bbrc.2020.01.135
Zacchi, Lucia F., Roche Recinos, Dinora, Otte, Ellen, Aitken, Campbell, Hunt, Tony, Sandford, Vanessa, Lee, Yih Yean, Schulz, Benjamin L. and Howard, Christopher B. (2020). S-trap eliminates cell culture media polymeric surfactants for effective proteomic analysis of mammalian cell bioreactor supernatants. Journal of Proteome Research, 19 (5), 2149-2158. doi: 10.1021/acs.jproteome.0c00106
Phung, Toan K., Zacchi, Lucia F. and Schulz, Benjamin L. (2020). DIALib: an automated ion library generator for data independent acquisition mass spectrometry analysis of peptides and glycopeptides. Molecular Omics, 16 (2), 100-112. doi: 10.1039/c9mo00125e
Delbaz, Ali, Chen, Mo, Jen, Freda E-C, Schulz, Benjamin L., Gorse, Alain-Dominique, Jennings, Michael P., St John, James A. and Ekberg, Jenny A K (2020). Neisseria meningitidis induces pathology-associated cellular and molecular changes in trigeminal Schwann cells. Infection and Immunity, 88 (4) e00955-19. doi: 10.1128/IAI.00955-19
Feder, Daniel, McGeary, Ross P., Mitić, Natasa, Lonhienne, Thierry, Furtado, Agnelo, Schulz, Benjamin L., Henry, Robert J., Schmidt, Susanne, Guddat, Luke W. and Schenk, Gerhard (2020). Structural elements that modulate the substrate specificity of plant purple acid phosphatases: avenues for improved phosphorus acquisition in crops. Plant Science, 294 110445, 110445. doi: 10.1016/j.plantsci.2020.110445
Knopf, Julia D., Landscheidt, Nina, Pegg, Cassandra L., Schulz, Benjamin L., Kühnle, Nathalie, Chao, Chao-Wei, Huck, Simon and Lemberg, Marius K. (2020). Intramembrane protease RHBDL4 cleaves oligosaccharyltransferase subunits to target them for ER-associated degradation. Journal of Cell Science, 133 (6) jcs243790, 1-16. doi: 10.1242/jcs.243790
Witham, Christopher M., Dassanayake, Hasindu G., Paxman, Aleshanee L., Stevens, Kofi L.P., Baklous, Lamprini, White, Paris F., Black, Amy L., Steuart, Robert F.L., Stirling, Colin J., Schulz, Benjamin L. and Mousley, Carl J. (2020). The conserved C-terminus of Sss1p is required to maintain the endoplasmic reticulum permeability barrier. Journal of Biological Chemistry, 295 (7), 2125-2134. doi: 10.1074/jbc.RA119.010378
Elango, Danila and Schulz, Benjamin L. (2019). Phase-variable glycosylation in nontypeable Haemophilus influenzae. Journal of Proteome Research, 19 (1) acs.jproteome.9b00657, 464-476. doi: 10.1021/acs.jproteome.9b00657
Tahir, Muhammad S., Nguyen, Loan T., Schulz, Benjamin L., Boe-Hansen, Gry A., Thomas, Milton G., Moore, Stephen S., Lau, Li Yieng and Fortes, Marina R S (2019). Proteomics recapitulates ovarian proteins relevant to puberty and fertility in Brahman heifers (Bos indicus L.). Genes, 10 (11) 923, 923. doi: 10.3390/genes10110923
Seib, Kate L., Haag, Andreas F., Oriente, Francesca, Fantappie, Laura, Borghi, Sara, Semchenko, Evgeny A., Schulz, Benjamin L., Ferlicca, Francesca, Taddei, Anna Rita, Giuliani, Marzia M., Pizza, Mariagrazia and Delany, Isabel (2019). The meningococcal vaccine antigen GNA2091 is an analogue of YraP and plays key roles in outer membrane stability and virulence. Faseb Journal, 33 (11), 12324-12335. doi: 10.1096/fj.201900669R
Zhuang, Aowen, Yap, Felicia Y. T., McCarthy, Domenica, Leung, Chris, Sourris, Karly C., Penfold, Sally A., Thallas-Bonke, Vicki, Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2019). Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion. Scientific Reports, 9 (1) 13664, 13664. doi: 10.1038/s41598-019-50221-0
Kerr, Edward D., Phung, Toan K., Caboche, Christopher H., Fox, Glen P., Platz, Greg J. and Schulz, Benjamin L. (2019). The intrinsic and regulated proteomes of barley seeds in response to fungal infection. Analytical Biochemistry, 580, 30-35. doi: 10.1016/j.ab.2019.06.004
Kerr, Edward D., Caboche, Christopher H. and Schulz, Benjamin L. (2019). Post-translational modifications drive protein stability to control the dynamic beer brewing proteome. Molecular and Cellular Proteomics, 18 (9), 1721-1731. doi: 10.1074/mcp.ra119.001526
Enculescu, Charmaine, Kerr, Edward D., Yeo, K. Y. Benjamin, Schenk, Gerhard, Fortes, Marina R. S. and Schulz, Benjamin L. (2019). Proteomics reveals profound metabolic changes in the alcohol use disorder brain. ACS Chemical Neuroscience, 10 (5), 2364-2373. doi: 10.1021/acschemneuro.8b00660
Zou, Wei, Schulz, Benjamin L., Tan, Xinle, Sissons, Mike, Warren, Frederick J., Gidley, Michael J. and Gilbert, Robert G. (2019). The role of thermostable proteinaceous α-amylase inhibitors in slowing starch digestion in pasta. Food Hydrocolloids, 90, 241-247. doi: 10.1016/j.foodhyd.2018.12.023
Gao, Shu-Hong, Ho, Jun Yuan, Fan, Lu, Nouwens, Amanda, Hoelzle, Robert D., Schulz, Benjamin, Guo, Jianhua, Zhou, Jizhong, Yuan, Zhiguo and Bond, Philip L. (2019). A comparative proteomic analysis of Desulfovibrio vulgaris Hildenborough in response to the antimicrobial agent free nitrous acid. Science of The Total Environment, 672, 625-633. doi: 10.1016/j.scitotenv.2019.03.442
Matsuda-Lennikov, Mami, Biancalana, Matthew, Zou, Juan, Ravell, Juan C., Zheng, Lixin, Kanellopoulou, Chrysi, Jiang, Ping, Notarangelo, Giulia, Jing, Huie, Masutani, Evan, Oler, Andrew J., Olano, Lisa Renee, Schulz, Benjamin L. and Lenardo, Michael J. (2019). Magnesium transporter 1 (MAGT1) deficiency causes selective defects in N-linked glycosylation and expression of immune-response genes. Journal of Biological Chemistry, 294 (37), 13638-13656. doi: 10.1074/jbc.RA119.008903
Liu, Guoquan, Gilding, Edward K., Kerr, Edward D., Schulz, Benjamin L., Tabet, Basam, Hamaker, Bruce R. and Godwin, Ian D. (2019). Increasing protein content and digestibility in sorghum grain with a synthetic biology approach. Journal of Cereal Science, 85, 27-34. doi: 10.1016/j.jcs.2018.11.001
Mu, Yuqing, Schulz, Benjamin L. and Ferro, Vito (2018). Applications of ion mobility-mass spectrometry in carbohydrate chemistry and glycobiology. Molecules, 23 (10) 2557, 2557. doi: 10.3390/molecules23102557
Kerr, Edward, McDiarmid, Duin, Fraser, James and Schulz, Benjamin (2018). Cell Wall and Whole Cell Proteomes Define Flocculation and Fermentation Behavior of Yeast. Fermentation, 4 (3) 80, 80. doi: 10.3390/fermentation4030080
Fortes, M. R.S., Zacchi, L. F., Nguyen, L. T., Raidan, F., Weller, M. M.D.C.A., Choo, J. J.Y., Reverter, A., Rego, J. P.A., Boe-Hansen, G. B., Porto-Neto, L. R., Lehnert, S. A., Cánovas, A., Schulz, B. L., Islas-Trejo, A., Medrano, J. F., Thomas, M. G. and Moore, S. S. (2018). Pre- and post-puberty expression of genes and proteins in the uterus of Bos indicus heifers: the luteal phase effect post-puberty. Animal Genetics, 49 (6), 539-549. doi: 10.1111/age.12721
Brockman, Kenneth L., Azzari, Patrick N., Branstool, M. Taylor, Atack, John M., Schulz, Benjamin L., Jen, Freda E.-C., Jennings, Michael P. and Bakaletz, Lauren O. (2018). Epigenetic regulation alters biofilm architecture and composition in multiple clinical isolates of nontypeable haemophilus influenzae. mBio, 9 (5) e01682-18. doi: 10.1128/mBio.01682-18
Nguyen, L. T., Zacchi, L. F., Schulz, B. L., Moore, S. S. and Fortes, M. R. S. (2018). Adipose tissue proteomic analyses to study puberty in Brahman heifers. Journal of Animal Science, 96 (6), 2392-2398. doi: 10.1093/jas/sky128
Soderholm, Amelia T., Barnett, Timothy C., Korn, Othmar, Rivera-Hernandez, Tania, Seymour, Lisa M., Schulz, Benjamin L., Nizet, Victor, Wells, Christine A., Sweet, Matthew J. and Walker, Mark J. (2018). Group A Streptococcus M1T1 intracellular infection of primary tonsil epithelial cells dampens levels of secreted IL-8 through the action of SpyCEP. Frontiers in Cellular and Infection Microbiology, 8 (MAY) 160, 160. doi: 10.3389/fcimb.2018.00160
Laloo, Andrew E., Wei, Justin, Wang, Dongbo, Narayanasamy, Shaman, Vanwonterghem, Inka, Waite, David, Steen, Jason, Kaysen, Anne, Heintz-Buschart, Anna, Wang, Qilin, Schulz, Benjamin, Nouwens, Amanda, Wilmes, Paul, Hugenholtz, Philip, Yuan, Zhiguo and Bond, Philip L. (2018). Mechanisms of persistence of the ammonia-oxidizing bacteria Nitrosomonas to the biocide free nitrous acid. Environmental science & technology, 52 (9), 5386-5397. doi: 10.1021/acs.est.7b04273
Prow, Natalie A., Mah, Marcus G., Deerain, Joshua M., Warrilow, David, Colmant, Agathe M. G., O'Brien, Caitlin A., Harrison, Jessica J., McLean, Breeanna J., Hewlett, Elise K., Piyasena, Thisun B. H., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Watterson, Daniel, Huang, Bixing, Schulz, Benjamin L., Webb, Cameron E., Johansen, Cheryl A., Chow, Weng K., Hobson-Peters, Jody, Cazier, Chris, Coffey, Lark L., Faddy, Helen M., Suhrbier, Andreas, Bielefeldt-Ohmann, Helle and Hall, Roy A. (2018). New genotypes of Liao ning virus (LNV) in Australia exhibit an insect-specific phenotype. The Journal of General Virology, 99 (4), 596-609. doi: 10.1099/jgv.0.001038
Tan, Xinle, Sullivan, Mitchell A., Nada, Sharif S., Deng, Bin, Schulz, Benjamin L. and Gilbert, Robert G. (2018). Proteomic investigation of the binding agent between liver glycogen beta particles. ACS Omega, 3 (4), 3640-3645. doi: 10.1021/acsomega.8b00119
Schulz, Benjamin L., Phung, Toan K., Bruschi, Michele, Janusz, Agnieszka, Stewart, Jeff, Meehan, John, Healy, Peter, Nouwens, Amanda S., Fox, Glen P. and Vickers, Claudia E. (2018). Process Proteomics of Beer Reveals a Dynamic Proteome with Extensive Modifications. Journal of Proteome Research, 17 (4), 1647-1653. doi: 10.1021/acs.jproteome.7b00907
Semenec, Lucie, Laloo, Andrew E., Schulz, Benjamin L., Vergara, Ismael A., Bond, Philip L. and Franks, Ashley E. (2018). Deciphering the electric code of geobacter sulfurreducens in cocultures with pseudomonas aeruginosa via SWATH-MS proteomics. Bioelectrochemistry, 119, 150-160. doi: 10.1016/j.bioelechem.2017.09.013
Arras, Samantha D. M., Ormerod, Kate L., Erpf, Paige E., Espinosa, Monica I., Carpenter, Alex C., Blundell, Ross D., Stowasser, Samantha R., Schulz, Benjamin L., Tanurdzic, Milos and Fraser, James A. (2017). Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic. Scientific Reports, 7 (1) 17918, 1-14. doi: 10.1038/s41598-017-18106-2
Stevens, Kofi L. P., Black, Amy L., Wells, Kelsi M., Yeo, K. Y. Benjamin, Steuart, Robert F. L., Stirling, Colin J., Schulz, Benjamin L. and Mousley, Carl J. (2017). Diminished Ost3-dependent N-glycosylation of the BiP nucleotide exchange factor Sil1 is an adaptive response to reductive ER stress. Proceedings of the National Academy of Sciences of the United States of America, 114 (47), 12489-12494. doi: 10.1073/pnas.1705641114
Zhuang, Aowen, Yap, Felicia Y. T., Bruce, Clinton, Leung, Chris, Plan, Manuel R., Sullivan, Mitchell A., Herath, Chandana, McCarthy, Domenica, Sourris, Karly C., Kantharidis, Phillip, Coughlan, Melinda T., Febbraio, Mark A. , Hodson, Mark P., Watt, Matthew J., Angus, Peter, Schulz, Benjamin L. and Forbes, Josephine M. (2017). Increased liver AGEs induce hepatic injury mediated through an OST48 pathway. Scientific Reports, 7 (1) 12292, 12292. doi: 10.1038/s41598-017-12548-4
Zacchi, Lucia F., Dittmar, John C., Mihalevic, Michael J., Shewan, Annette M., Schulz, Benjamin L., Brodsky, Jeffrey L. and Bernstein, Kara A. (2017). Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinA Delta E. Disease Models & Mechanisms, 10 (9), 1129-1140. doi: 10.1242/dmm.029926
Medus, Maximo L., Gomez, Gabriela E., Zacchi, Lucia F., Couto, Paula M., Labriola, Carlos A., Labanda, Maria S., Bielsa, Rodrigo Corti, Clérico, Eugenia M., Schulz, Benjamin L. and Caramelo, Julio J. (2017). N-glycosylation triggers a dual selection pressure in eukaryotic secretory proteins. Scientific Reports, 7 (1) 8788, 8788. doi: 10.1038/s41598-017-09173-6
Colmant, Agathe M. G., Hobson-Peters, Jody, Bielefeldt-Ohmann, Helle, van den Hurk, Andrew F., Hall-Mendelin, Sonja, Chow, Weng Kong, Johansen, Cheryl A., Fros, Jelke, Simmonds, Peter, Watterson, Daniel, Cazier, Chris, Etebari, Kayvan, Asgari, Sassan, Schulz, Benjamin L., Beebe, Nigel, Vet, Laura J., Piyasena, Thisun B. H., Nguyen, Hong-Duyen, Barnard, Ross T. and Hall, Roy A. (2017). A new clade of insect-specific flaviviruses from Australian Anopheles mosquitoes displays species-specific host-restriction. mSphere, 2 (4) e00262-17, 1-19. doi: 10.1128/mSphere.00262-17
Lo, Alvin W., Moriel, Danilo G., Phan, Minh-Duy, Schulz, Benjamin L., Kidd, Timothy J., Beatson, Scott A. and Schembri, Mark A. (2017). 'Omic' approaches to study Uropathogenic Escherichia coli virulence. Trends in Microbiology, 25 (9), 729-740. doi: 10.1016/j.tim.2017.04.006
Day, Christopher J. , Paton, Adrienne W., Higgins, Melanie A. , Shewell, Lucy K. , Jen, Freda E.-C., Schulz, Benjamin L., Herdman, Brock P., Paton, James C. and Jennings, Michael P. (2017). Structure aided design of a Neu5Gc specific lectin. Scientific Reports, 7 (1) 1495, 1495. doi: 10.1038/s41598-017-01522-9
Arras, Samantha D. M., Chitty, Jessica L., Wizrah, Maha S. I., Erpf, Paige E., Schulz, Benjamin L., Tanurdzic, Milos and Fraser, James A. (2017). Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans. Scientific Reports, 7 (1) 46567, 46567.1-46567.14. doi: 10.1038/srep46567
O'Brien, Caitlin A., McLean, Breeanna J., Colmant, Agathe M. G., Harrison, Jessica J., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Johansen, Cheryl A., Watterson, Daniel, Bielefeldt-Ohmann, Helle, Newton, Natalee D., Schulz, Benjamin L., Hall, Roy A. and Hobson-Peters, Jody (2017). Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia. Evolutionary Bioinformatics, 13, 1176934317691269. doi: 10.1177/1176934317691269
Zhang, Xi, Walsh, Terry, Atherton, John J., Kostner, Karam, Schulz, Benjamin and Punyadeera, Chamindie (2017). Identification and validation of a salivary protein panel to detect heart failure early. Theranostics, 7 (18) 21727, 4350-4358. doi: 10.7150/thno.21727
Yeo, K. Y. Benjamin, Chrysanthopoulos, Panangiotis K., Nouwens, Amanda S., Marcellin, Esteban and Schulz, Benjamin L. (2016). High performance targeted mass spectrometry with precision data independent acquisition reveals site-specific glycosylation macroheterogeneity. Analytical Biochemistry, 510, 106-113. doi: 10.1016/j.ab.2016.06.009
Tan, Xinle, Sullivan, Mitchell A., Gao, Fei, Li, Shihan, Schulz, Benjamin L. and Gilbert, Robert G. (2016). A new non-degradative method to purify glycogen. Carbohydrate Polymers, 147, 165-170. doi: 10.1016/j.carbpol.2016.04.009
Kerr, Edward D. and Schulz, Benjamin L. (2016). Vegemite beer: yeast extract spreads as nutrient supplements to promote fermentation. Peerj, 4 (10) e2271, e2271. doi: 10.7717/peerj.2271
Peak, Ian R., Chen, Adrienne, Jen, Freda E. -C., Jennings, Courtney, Schulz, Benjamin L., Saunders, Nigel J., Khan, Arshad, Seifert, H. Steven and Jennings, Michael P. (2016). Neisseria meningitidis lacking the major porins PorA and PorB is viable and modulates apoptosis and the oxidative burst of neutrophils. Journal of Proteome Research, 15 (8), 2356-2365. doi: 10.1021/acs.jproteome.5b00938
Thaysen-Andersen, Morten, Packer, Nicolle H. and Schulz, Benjamin L. (2016). Maturing glycoproteomics technologies provide unique structural insights into the N-glycoproteome and its regulation in health and disease. Molecular and Cellular Proteomics, 15 (6), 1773-1790. doi: 10.1074/mcp.O115.057638
Zacchi, Lucia F. and Schulz, Benjamin L. (2016). SWATH-MS glycoproteomics reveals consequences of defects in the glycosylation machinery. Molecular and Cellular Proteomics, 15 (7), 2435-2447. doi: 10.1074/mcp.M115.056366
Caragata, Michael, Shah, Alok K., Schulz, Benjamin L., Hill, Michelle M. and Punyadeera, Chamindie (2016). Enrichment and identification of glycoproteins in human saliva using lectin magnetic bead arrays. Analytical Biochemistry, 497, 76-82. doi: 10.1016/j.ab.2015.11.024
Zhang, Xi, Schulz, Benjamin L. and Punyadeera, Chamindie (2016). The current status of heart failure diagnostic biomarkers. Expert Review of Molecular Diagnostics, 16 (4), 487-500. doi: 10.1586/14737159.2016.1144474
Zacchi, Lucia F. and Schulz, Benjamin L. (2015). N-glycoprotein macroheterogeneity: biological implications and proteomic characterization.. Glycoconjugate Journal, 33 (3), 1-18. doi: 10.1007/s10719-015-9641-3
Powell, Prudence O., Sullivan, Mitchell A., Sheehy, Joshua J., Schulz, Benjamin L., Warren, Frederick J. and Gilbert, Robert G. (2015). Correction: Acid hydrolysis and molecular density of phytoglycogen and liver glycogen helps understand the bonding in glycogen a (composite) particles. PLoS One, 10 (7) e0134065, e0134065. doi: 10.1371/journal.pone.0134065
Xu, Ying, Bailey, Ulla-Maja and Schulz, Benjamin L. (2015). Automated measurement of site-specific N-glycosylation occupancy with SWATH-MS. Proteomics, 15 (13), 2177-2186. doi: 10.1002/pmic.201400465
Brennan, Timothy C. R., Williams, Thomas C., Schulz, Benjamin L., Palfreyman, Robin W., Kroemer, Jens O. and Nielsen, Lars K. (2015). Evolutionary engineering improves tolerance for replacement jet fuels in Saccharomyces cerevisiae. Applied and Environmental Microbiology, 81 (10), 3316-3325. doi: 10.1128/AEM.04144-14
Deng, Bin, Sullivan, Mitchell A., Li, Jialun, Tan, Xinle, Zhu, Chengjun, Schulz, Benjamin L. and Gilbert, Robert G. (2015). Molecular structure of glycogen in diabetic liver. Glycoconjugate Journal, 32 (3-4), 113-118. doi: 10.1007/s10719-015-9578-6
Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Schulz, Benjamin L. and Fraser, James A. (2015). A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.. PLoS One, 10 (4) e0122916, e0122916-e0122916. doi: 10.1371/journal.pone.0122916
Sullivan, Mitchell A., Li, Shihan, Aroney, Samuel T.N., Deng, Bin, Li, Cheng, Roura, Eugeni, Schulz, Benjamin L., Harcourt, Brooke E., Forbes, Josephine M. and Gilbert, Robert G. (2015). A rapid extraction method for glycogen from formalin-fixed liver. Carbohydrate Polymers, 118, 9-15. doi: 10.1016/j.carbpol.2014.11.005
Powell, Prudence O., Sullivan, Mitchell A., Sheehy, Joshua J., Schulz, Benjamin L., Warren, Frederick J. W. and Gilbert, Robert G. (2015). Acid Hydrolysis and Molecular Density of Phytoglycogen and Liver Glycogen Helps Understand the Bonding in Glycogen α (Composite) Particles.. PLoS One, 10 (3) e0121337, e0121337-e0121337. doi: 10.1371/journal.pone.0121337
Orellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015). High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 (2), 609-618. doi: 10.1021/pr501027c
Jamaluddin, M. Fairuz B., Bailey, Ulla-Maja and Schulz, Benjamin L. (2014). Oligosaccharyltransferase Subunits Bind Polypeptide Substrate to Locally Enhance N-glycosylation. Molecular and Cellular Proteomics, 13 (12), 3286-3293. doi: 10.1074/mcp.M114.041178
Loibl, Martin, Wunderle, Lina, Hutzler, Johannes, Schulz, Benjamin L., Aebi, Markus and Strahl, Sabine (2014). Protein O-mannosyltransferases associate with the translocon to modify translocating polypeptide chains. Journal of Biological Chemistry, 289 (12), 8599-8611. doi: 10.1074/jbc.M113.543116
Xu, Ying, Bailey, Ulla-Maja, Punyadeera, Chamindie and Schulz, Benjamin L. (2014). Identification of salivary N-glycoproteins and measurement of glycosylation site occupancy by boronate glycoprotein enrichment and liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Communications In Mass Spectrometry, 28 (5), 471-482. doi: 10.1002/rcm.6806
Gawthorne, Jayde A., Tan, Nikki Y., Bailey, Ulla-Maja, Davis, Margaret R., Wong, Linette W., Naidu, Ranjitha, Fox, Kate L., Jennings, Michael P. and Schulz, Benjamin L. (2014). Selection against glycosylation sites in potential target proteins of the general HMWC N-glycosyltransferase in Haemophilus influenzae. Biochemical and Biophysical Research Communications, 445 (3), 633-638. doi: 10.1016/j.bbrc.2014.02.044
Tan, Nikki Y., Bailey, Ulla-Maja, Jamaluddin, M Fairuz, Mahmud, S Halimah Binte, Raman, Suresh C. and Schulz, Benjamin L. (2014). Sequence-based protein stabilization in the absence of glycosylation. Nature Communications, 5 (3099) 3099, 1-7. doi: 10.1038/ncomms4099
Soleh, Muhammad Tarmizi, Foo, Jared Yong Yang, Bailey, Ulla-Maja, Tan, Nikki Yi, Wan, Yunxia, Cooper-White, Justin, Schulz, Benjamin Luke and Punyadeera, Chamindie (2014). A rapid and cost-effective method of producing recombinant proBNP and NT-proBNP variants in Escherichia coli for immunoassay of heart failure. Biotechnology Letters, 36 (1), 133-140. doi: 10.1007/s10529-013-1341-0
Barnett, Timothy C., Liebl, David, Seymour, Lisa M., Gillen, Christine M., Lim, Jin Yan, LaRock, Christopher N., Davies, Mark R., Schulz, Benjamin L., Nizet, Victor, Teasdale, Rohan D. and Walker, Mark J. (2013). The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication. Cell Host and Microbe, 14 (6), 675-682. doi: 10.1016/j.chom.2013.11.003
Foo, Jared Yong Yang, Wan, Yunxia, Schulz, Benjamin L., Kostner, Karam, Atherton, John, Cooper-White, Justin, Dimeski, Goce and Punyadeera, Chamindie (2013). Circulating Fragments of N-Terminal Pro-B-Type Natriuretic Peptides in Plasma of Heart Failure Patients. Clinical Chemistry, 59 (10), 1523-1531. doi: 10.1373/clinchem.2012.200204
Schulz, Benjamin L., Cooper-White, Justin and Punyadeera, Chamindie K. (2013). Saliva proteome research: current status and future outlook. Critical Reviews in Biotechnology, 33 (3), 246-259. doi: 10.3109/07388551.2012.687361
Schulz, Benjamin L., Jen, Freda E. C., Power, Peter M., Jones, Christopher E., Fox, Kate L., Ku, Shan C., Blanchfield, Joanne T. and Jennings, Michael P. (2013). Identification of bacterial protein O-Oligosaccharyltransferases and their glycoprotein substrates. PLoS One, 8 (5) e62768, e62768.1-e62768.11. doi: 10.1371/journal.pone.0062768
Jen, Freda E. -C., Warren, Matthew J., Schulz, Benjamin L., Power, Peter M., Swords, W. Edward, Weiser, Jeffery N., Apicella, Michael A., Edwards, Jennifer L. and Jennings, Michael P. (2013). Dual Pili Post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells. PLoS Pathogens, 9 (5) e1003377, e1003377.1-e1003377.16. doi: 10.1371/journal.ppat.1003377
Yusuf, Siti N. H. Mohd, Bailey, Ulla-Maja, Tan, Nikki Y., Jamaluddin, Muhammad Fairuz and Schulz, Benjamin L. (2013). Mixed disulfide formation in vitro between a glycoprotein substrate and yeast oligosaccharyltransferase subunits Ost3p and Ost6p. Biochemical and Biophysical Research Communications, 432 (3), 438-443. doi: 10.1016/j.bbrc.2013.01.128
Bailey, Ulla-Maja and Schulz, Benjamin L. (2013). Deglycosylation systematically improves N-glycoprotein identification in liquid chromatography-tandem mass spectrometry proteomics for analysis of cell wall stress responses in Saccharomyces cerevisiae lacking Alg3p. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 923-924, 16-21. doi: 10.1016/j.jchromb.2013.01.026
Jen, Freda E. -C., Jones, Christopher E., Wilson, Jennifer C., Schulz, Benjamin L. and Jennings, Michael P. (2013). Substrate recognition of a structure motif for phosphorylcholine post-translational modification in Neisseria meningitidis. Biochemical and Biophysical Research Communications, 431 (4), 808-814. doi: 10.1016/j.bbrc.2012.12.088
Shewell, Lucy K., Ku, Shan C., Schulz, Benjamin L., Jen, Freda E. -C., Mubaiwa, Tsitsi D., Ketterer, Margaret R., Apicella, Michael A. and Jennings, Michael P. (2013). Recombinant truncated AniA of pathogenic Neisseria elicits a non-native immune response and functional blocking antibodies. Biochemical and Biophysical Research Communications, 431 (2), 215-220. doi: 10.1016/j.bbrc.2012.12.132
Bailey, Ulla-Maja, Punyadeera, Chamindie, Cooper-White, Justin J. and Schulz, Benjamin L. (2012). Analysis of the extreme diversity of salivary alpha-amylase isoforms generated by physiological proteolysis using liquid chromatography-tandem mass spectrometry. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 911, 21-26. doi: 10.1016/j.jchromb.2012.10.023
Bailey, Ulla-Maja, Jamaluddin, Muhammad Fairuz and Schulz, Benjamin L. (2012). Analysis of congenital disorder of glycosylation-Id in a yeast model system shows diverse site-specific under-glycosylation of glycoproteins. Journal of Proteome Research, 11 (11), 5376-5383. doi: 10.1021/pr300599f
Issa, Samah M. A., Schulz, Benjamin L., Packer, Nicolle H. and Karlsson, Niclas G. (2011). Analysis of mucosal mucins separated by SDS-urea agarose polyacrylamide composite gel electrophoresis. Electrophoresis, 32 (24), 3554-3563. doi: 10.1002/elps.201100374
Jamaluddin, M. Fairuz B., Bailey, Ulla-Maja, Tan, Nikki Y. J., Stark, Anthony P. and Schulz, Benjamin L. (2011). Polypeptide binding specificities of Saccharomyces cerevisiae oligosaccharyltransferase accessory proteins Ost3p and Ost6p. Protein Science, 20 (5), 849-855. doi: 10.1002/pro.610
Zalucki, Yaramah M., Jones, Christopher E., Ng, Preston S. K., Schulz, Benjamin L. and Jennings, Michael P. (2010). Signal sequence non-optimal codons are required for the correct folding of mature maltose binding protein. BBA: Biomembranes, 1798 (6), 1244-1249. doi: 10.1016/j.bbamem.2010.03.010
Schwarz, Flavio, Huang, Wei, Li, Cishan, Schulz, Benjamin L., Lizak, Christian, Palumbo, Alessandro, Numao, Shin, Neri, Dario, Aebi, Markus and Wang, Lai-Xi (2010). A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation. Nature Chemical Biology, 6 (4), 264-266. doi: 10.1038/NCHEMBIO.314
Izquierdo, Luis, Schulz, Benjamin L., Rodrigues, João A., Güther, Maria Lucia S., Procter, James B., Barton, Geoffrey J., Aebi, Markus and Ferguson, Michael A. J. (2009). Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases. EMBO Journal, 28 (17), 2650-2661. doi: 10.1038/emboj.2009.203
Ahuja, Umesh, Kjelgaard, Peter, Schulz, Benjamin L., Thony-Meyer, Linda and Hederstedt, Lars (2009). Haem-delivery proteins in cytochrome c maturation System II. Molecular Microbiology, 73 (6), 1058-1071. doi: 10.1111/j.1365-2958.2009.06833.x
Schulz, Benjamin L., Stirnimann, Christian U., Grimshaw, John P. A., Brozzo, Maurice S., Fritsch, Fabienne, Mohorko, Elisabeth, Capitani, Guido, Glockshuber, Rudi, Grütter, Markus G. and Aebi, Markus (2009). Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. PNAS, 106 (27), 11061-11066. doi: 10.1073/pnas.0812515106
Schulz, Benjamin L. and Aebi, Markus (2009). Analysis of glycosylation site occupancy reveals a role for Ost3p and Ost6p in site-specific N-glycosylation efficiency. Molecular and Cellular Proteomics, 8 (2), 357-364. doi: 10.1074/mcp.M800219-MCP200
Ku, S.C., Schulz, B.L., Power, P.M. and Jennings, M.P. (2009). The pilin O-glycosylation pathway of pathogenic Neisseria is a general system that glycosylates AniA, an outer membrane nitrite reductase. Biochemical and Biophysical Research Communications, 378 (1), 84-89. doi: 10.1016/j.bbrc.2008.11.025
Nasab, Farnoush Parsaie, Schulz, Benjamin L., Gamarro, Francisco, Parodi, Armando J. and Aebi, Markus (2008). All in One: Leishmania major STT3 Proteins Substitute for the Whole Oligosaccharyltransferase Complex in Saccharomyces cerevisiae. Molecular Biology of the Cell, 19 (9), 3758-3768. doi: 10.1091/mbc.E08-05-0467
Schulz, Benjamin L., Sloane, Andrew J., Robinson, Leanne J., Prasad, Sindhu S., Lindner, Robyn A., Robinson, Michael, Bye, Peter T., Nielson, Dennis W., Harry, Jenny L., Packer, Nicolle H. and Karlsson, Niclas G. (2007). Glycosylation of sputum mucins is altered in cystic fibrosis patients. Glycobiology, 17 (7), 698-712. doi: 10.1093/glycob/cwm036
Schulz, Benjamin L., Laroy, Wouter and Callewaert, Nico (2007). Clinical laboratory testing in human medicine based on the detection of glycoconjugates. Current Molecular Medicine, 7 (4), 397-416. doi: 10.2174/156652407780831629
Kowarik, Michael, Numao, Shin, Feldman, Mario F., Schulz, Benjamin L., Callewaert, Nico, Kiermaier, Eva, Catrein, Ina and Aebi, Markus (2006). N-Linked glycosylation of folded proteins by the bacterial oligosaccharyl transferase. Science, 314 (5802), 1148-1150. doi: 10.1126/science.1134351
Herbert, Ben R., Grinyer, Jasmine, McCarthy, John T., Isaacs, Mitchell, Harry, Elizabeth J., Nevalainen, Helena, Traini, Mathew D., Hunt, Sybille, Schulz, Ben, Laver, Matthew, Goodall, Anthony R., Packer, Joanne, Harry, Jenny L. and Williams, Keith L. (2006). Improved 2-DE of microorganisms after acidic extraction. Electrophoresis, 27 (8), 1630-1640. doi: 10.1002/elps.200500753
Kowarik, Michael, Young, N. Martin, Numao, Shin, Schulz, Benjamin L., Hug, Isabelle, Callewaert, Nico, Mills, Dominic C., Watson, David C., Hernandez, Marcela, Kelly, John F., Wacker, Michael and Aebi, Markus (2006). Definition of the bacterial N-glycosylation site consensus sequence. The EMBO Journal, 25 (9), 1957-1966. doi: 10.1038/sj.emboj.7601087
Karlsson, Niclas G., Schulz, Benjamin L., Packer, Nicolle H. and Whitelock, John M. (2005). Use of graphitised carbon negative ion LC-MS to analyse enzymatically digested glycosaminoglycans. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 824 (1-2), 139-147. doi: 10.1016/j.jchromb.2005.07.014
Thomsson, Kristina A., Schulz, Benjamin L., Packer, Nicolle H. and Karlsson, Niclas G. (2005). MUC5B glycosylation in human saliva reflects blood group and secretor status. Glycobiology, 15 (8), 791-804. doi: 10.1093/glycob/cwi059
Schulz, Benjamin L., Sloane, Andrew J., Robinson, Leanne J., Sebastian, Lucille T., Glanville, Allan R., Song, Yuanlin, Verkman, Alan S., Harry, Jenny L., Packer, Nicolle H. and Karlsson, Niclas G. (2005). Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions. Biochemical Journal, 387 (3), 911-919. doi: 10.1042/BJ20041641
Karlsson, Niclas G., Schulz, Benjamin L. and Packer, Nicolle H. (2004). Structural determination of neutral O-linked oligosaccharide alditols by negative ion LC-electrospray-MS. Journal of the American Society for Mass Spectrometry, 15 (5), 659-672. doi: 10.1016/j.jasms.2004.01.002
Joshi, Hiren J., Harrison, Mathew J., Schulz, Benjamin L., Cooper, Catherine A., Packer, Nicolle H. and Karlsson, Niclas G. (2004). Development of a mass fingerprinting tool for automated interpretation of oligosaccharide fragmentation data. Proteomics, 4 (6), 1650-1664. doi: 10.1002/pmic.200300784
Schulz, Benjamin L., Oxley, David, Packer, Nicolle H. and Karlsson, Niclas G. (2002). Identification of two highly sialylated human tear fluid DMBT1 ssoforms: Major high molecular weight glycoproteins in human tears. Biochemical Journal, 366 (2), 1-29. doi: 10.1042/BJ20011876
Schulz, Benjamin L., Packer, Nicolle H. and Karlsson, Niclas G. (2002). Small-scale analysis of o-linked oligosaccharides from glycoproteins and mucins separated by gel electrophoresis. Analytical Chemistry, 74 (23), 6088-6097. doi: 10.1021/ac025890a
Wilson, Nicole L., Schulz, Benjamin L., Karlsson, Niclas G. and Packer, Nicolle H. (2002). Sequential analysis of N- and O-Linked Glycosylation of 2D-PAGE separated glycoproteins. Journal of Proteome Research, 1 (6), 521-529. doi: 10.1021/pr025538d
Conference Papers
Pegg, Cassandra L., Phung, Toan K. and Schulz, Benjamin L. (2017). Site-specific glycosylation of viral surface proteins using mass spectrometry. Annual Meeting of the Society for Glycobiology , Portland, OR, United States, 05-08 November 2017. Cary, NC, United States: Oxford University Press. doi: 10.1093/glycob/cwx086
Zhang, X. Xi, Schulz, B., Walsh, T., Atherton, J., Kostner, K. and Punyadeera, C. (2017). Saliva: linking oral health with heart failure. Heart Failure 2017 and the 4th World Congress on Acute Heart Failure, Paris, France, 29 April - 2 May 2017. Oxford, United Kingdom: John Wiley & Sons.
Tan, Xinle, Deng, Bin, Jiang, Xiaoyin, Zhang, Peng, Hu, Zhenxia, Li, Enpeng, Sullivan, Mitchell A., Schulz, Benjamin L. and Gilbert, Robert G. (2016). Glycogen: Higher -Level Molecular Structure and Diabetes. 12th International Conference on Polysaccharides-Glycoscience, Prague Czech Republic, 19-21 October 2016. Prague Czech Republic: Czech Chemical Society.
Tan, Nikki, Bailey, Ulla-Maja, Jamaluddin, Fairuz, Mahmud, Siti, Raman, Suresh and Schulz, Benjamin (2014). Give up sugar with this one weird trick!. Joint Meeting of the Society for Glycobiology (SFG) and the Japanese Society of Carbohydrate Research (JSCR), Honolulu, HI United States, 16-19 November 2014. Cary, NC United States: Oxford University Press. doi: 10.1093/glycob/cwu107
Zhuang, A., Sourris, K. C, Harcourt, B. E, Penfold, S. A., Fotheringham, A. K., McCarthy, D., Schulz, B. and Forbes, J. M. (2014). Ager1 overexpression in glomerular podocytes results in renal disease which is exacerbated by diabetes. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne VIC, Australia, 25 - 27 August 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301
Karlsson, NG, Schulz, BL, Wilson, NL and Packer, NH (2004). Exploring the role of the glycosylation of mucins in the defence against pathogens in the respiratory and gastrointestinal systems. Joint Meeting of the Society-for-Glycobiology/Japanese-Society-for-Carbohydrate-Research, Honolulu Hi, Nov 17-20, 2004. CARY: OXFORD UNIV PRESS INC.