Safer viruses for vaccine research and diagnosis

12 Dec 2019
Flavivirus
A 3D reconstruction of a chimeric viral particle. Proteins on the virus surface have been coloured using a rainbow gradient to represent the many possible viruses that could be presented using this system. This image was developed by UQ’s Dr Daniel Watterson.

A new technology to produce safer ‘hybrid’ viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland.

Researchers from UQ and QIMR Berghofer Medical Research Institute have exploited the benign characteristics of the Binjari virus – inert to humans – to produce ‘dangerous looking’ mosquito-borne viruses such as Zika and dengue, but which cannot grow in humans or animals.

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