Title: TIR domain-mediated signalling by cooperative higher-order assembly formation

Speaker:  Prof Bostjan Kobe (SCMB)

Bio: Bostjan Kobe is a Professor of Structural Biology and NHMRC Investigator at SCMB. He received a BSc degree in chemistry at the University of Ljublijana, Slovenia, and a PhD degree in biochemistry and biophysics at the University of Texas Southwestern Medical Center at Dallas, USA. He received the 2001 Minister's Prize for Achievement in Life Sciences, the 2009 ASBMB Roche Medal, the 2018 ASBMB Beckman Coulter Discovery Award, and was named Slovenian Ambassador of Science in 2020. He is a Fellow of the Australian Academy of Science since 2018. He has 309 publications, >26,600 citations and h-index of 80. He is a Co-Editor of Acta Cryst Section D Structural Biology. His laboratory combines X-ray crystallography and cryo-electron microscopy, with molecular biology, biophysical and computational techniques to understand structure-function relationships in proteins. Recent biological focus has been on understanding proteins involved in infection and immunity, particularly proteins containing TIR (Toll/interleukin-1 receptor) domains.

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Seminars cover all aspects of chemistry and molecular biosciences and are delivered by visiting national and international academics. PhD completion seminars are also incorporated into the program.

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