Mass spectrometry is one of the most valuable tools in chemistry and biological chemistry.

The technique facilitates measurement of the mass of molecules and fragments with extraordinary sensitivity, speed and accuracy.

It allows accurate mass, identification, characterisation and quantification of molecules.

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Contact us for more information, including advice on sample preparation or experimental design:


    • Structural determination from high-resolution masses of small molecules.
    • Fragmentation to provide characterisation and identification of molecules.
    • LC-MS/MS to provide separation and identification.
    • Quantification of molecules (relative and absolute).

    Equipment and location


    BRUKER MicrOTof-Q

    The BRUKER MicrOTof-Q with DIONEX UltiMate 3000 HPLC is as an accurate mass instrument with ESI source, both accurate mass and identification of pure samples via looped injection and complex mixture analysis via the DIONEX UltiMate 3000 micro LC system.

    It provides a combination of high-mass accuracy, resolution and sensitivity in LC-MS mode and wide dynamic range for ultra-stable accurate mass.

    Thermo LCQ Fleet Ion Trap

    The Thermo LCQ Fleet Ion Trap serves as a low-resolution (nominal mass) student walk-up instrument in ESI/APCI mode via looped injector or isocratic pump. MSn capability provides an added dimension for structural elucidation and confirmation. 

    The LCQ MS in conjunction with the DIONEX UltiMate 3000 micro LC system provides online fractionation of complex mixtures and allows quantification (relative and absolute) of molecules through Multiple Reaction Monitoring Ionisation. Source: ESI


    Our associated data analysis software includes the NIST 14 spectral library, and software for compound searching. 


    Chemistry Building (Building 68 ), Room 102

    Sample requirements

    You'll need pure samples for infusions (syringe injections). You can submit an aliquot (1ml) of sample (10uM) in a suitable solvent (eg methanol or acetonitrile) or as a dry powder.

    For more complex samples requiring LCMS or LC-MS/MS analysis, you may need a more concentrated sample, depending on the sample's level of complexity and analysis. 

    Discuss your requirements with us prior to submission. 

    Charges and considerations


    External users

    Rates: $40 per sample, capped at $3000 per year.

    Note: we may charge extra fees for LCMS analyses to cover the use of high-quality MS-grade solvents and additional consumables.

    UQ users

    Contact us for internal rates.


    UQ users have priority of access.

    We can provide training for both low- and high-resolution instruments if you anticipate being a regular user.

    For one-off samples or infrequent users, we'll perform analyses for you.

    You'll need to undertake the relevant building and other inductions before using equipment.